Results 61 to 70 of about 1,330 (217)
For most patients with chronic, progressive illnesses, maintaining good quality of life (QoL), with preserved functional capacity, is just as crucial as prolonging survival. Patients with heart failure (HF) experience much worse QoL and effort intolerance than both the general population and people with other chronic conditions, since they present a ...
Maurizio Volterrani+21 more
wiley +1 more source
Baseline characteristics for the vericiguat global study in participants with chronic heart failure (VICTOR) trial. ARNI, angiotensin receptor/neprilysin inhibitor; CRT, cardiac resynchronization therapy; eGFR, estimated glomerular filtration rate; GDMT, guideline‐directed medical therapy; HF, heart failure; HFrEF, heart failure with reduced ejection ...
Clara I. Saldarriaga+21 more
wiley +1 more source
Abstract Introduction Oral metolazone and intravenous (IV) chlorothiazide have comparable diuretic efficacy and safety, although IV chlorothiazide is significantly more expensive. The use of electronic health record (EHR)‐based choice architecture interventions on the efficient use of diuretics remains unexplored.
Joshua A. Jacobs+13 more
wiley +1 more source
ATAC‐seq in Emerging Model Organisms: Challenges and Strategies
Principle of ATAC‐seq (left), overview of arthropod species with published ATAC‐seq data (middle), summary of experimental design (right). ABSTRACT The Assay for Transposase‐Accessible Chromatin with sequencing (ATAC‐seq) is a versatile and widely utilized method for identifying potential regulatory regions, such as promoters and enhancers, within a ...
Duğçar Ebrar Erdoğan+13 more
wiley +1 more source
Under‐display camera (UDC) enables full‐screen displays but degrades facial recognition accuracy due to diffraction‐induced distortions. This paper introduces three UDC face recognition datasets generated using a GAN trained on synthetic and real‐world images with flares.
Kyusu Ahn, Chanwoo Park, Jaejin Lee
wiley +1 more source
ABSTRACT Background and Objectives Identification of colorectal cancer (CRC) patients at high risk of recurrence could be of substantial clinical use. We evaluated the association of ctDNA status, using a tumor‐informed assay, with recurrence‐free survival (RFS). Methods Stage III CRC patients were enrolled between 2016 and 2020.
Brenda Diergaarde+25 more
wiley +1 more source
Evaluation of Arclight Frugal Smartphone Video Otoscopy
Frugal innovations are essential in low‐resource settings to provide cost‐effective medical solutions without compromising functionality. The Arclight, which functions as both an ophthalmoscope and an otoscope, is an effective, low‐cost tool for (video) ear examinations in low‐resource settings.
Christoph R. Buhr+7 more
wiley +1 more source
Multidrug resistant Pseudomonas (P.) aeruginosa is detected in many infected wounds and is challenging to treat with antibiotics. As an alternative, this work incorporates anti‐P. aeruginosa Neko phages into electrospun fibres to explore their potential for treating infected wounds.
Tian Ju+7 more
wiley +1 more source
ABSTRACT Proteolysis is an irreversible posttranslational modification with immense biological impact. Owing to its high disease significance, there is growing interest in investigating proteolysis on the proteome scale, termed degradomics. We developed ‘Database of Identified Cleavage sites Endemic to Disease states’ (DICED; https://diced.lerner.ccf ...
Jayadev Joshi+5 more
wiley +1 more source
A Non‐Metaproteomics Researchers’ View on Metaproteomics in Microbiome Research
ABSTRACT Metaproteomics, an emerging field among the omic techniques, holds great promise for unraveling the function of microbiomes in host health and our environment. Metaproteomics can also be a valuable addition to multiomics studies of the microbiome, complementing genome‐resolved metagenomics, metatranscriptomics, and metabolomics.
Velma T. E. Aho+5 more
wiley +1 more source