Results 81 to 90 of about 1,837 (160)

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

Biotechnology and Applied Biochemistry, Volume 73, Issue 5, Page 2457-2481, October 2026.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva, Caio Patrício de Souza Sena, Davi Serradella Vieira, Magdi E. A. Zaki, Leow Chiuan Yee, Shahina Akter, Umberto Laino Fulco, Jonas Ivan Nobre Oliveira, João Firmino Rodrigues‐Neto   +8 more
wiley   +1 more source

Unsupervised multimodal deep learning for galaxy morphology taxonomy: integrating ConvNeXtEmbeddings and morphological parameters for scalable survey science. [PDF]

Sci Rep
Selim IM, Farahat AS, Basmsm LH, El-Hameed AMA.   +3 more
europepmc   +1 more source

Form flows function: Learner‐centered game Re‐design in a STEM classroom

British Educational Research Journal, Volume 52, Issue 5, Page 3322-3340, October 2026.
Abstract Re‐designing games facilitates interest‐driven learning and immerses learners in systems thinking. However, there are limited studies exploring how the form and function of tabletop games influence learners' design decisions and learning experiences. To address this gap, we conducted a mixed‐methods study in a STEM classroom in western Canada.
Farzan Baradaran Rahimi, Beaumie Kim, Shima Dadkhahfard   +2 more
wiley   +1 more source

Overmassive black holes and little red dots naturally form in simulations. [PDF]

Nature
Chon S, Hirano S, Ishiyama T, Chang SJ, Springel V.   +4 more
europepmc   +1 more source

An Integrated Transient Expression and UPLC‐PDA Approach for Functional Genomics and Metabolic Analysis of Cannabis sativa

Biotechnology Journal, Volume 21, Issue 10, October 2026.
Graphical Abstract and Lay Summary Cannabis research is limited by a lack of efficient tools for studying gene function and metabolism. We developed two rapid, high‐efficiency methods for transient gene expression in high‐THC Cannabis and a simple, cost‐effective method to measure cannabinoids and cannflavins.
Sarah Pullano, Aida Shahabi, Parmis Shariat Torbaghani, Ivan Monsalvo, Madison Sandler, Adam Sumner, Alex Harris, David Haak, Bastiaan Bargmann, Nik Kovinich   +9 more
wiley   +1 more source

Genome‐Wide Identification and Structural Characterization of Secondary Metabolite Biosynthetic Gene Clusters in African Baobab (Adansonia digitata)

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Genome‐wide computational analysis of the African baobab (Adansonia digitata) identifies 50 candidate biosynthetic gene clusters spanning terpene, polyketide, cyclopeptide, and lignan pathways, including nine BURP‐domain clusters linked to putative chemical defense.
Ahmed A. Elshikh, Ahmed S. Kabbashi, Imtenan M. Musa   +2 more
wiley   +1 more source

Molecular Divergence Between Two Geographically Overlapping Cryptic Crickets: Loxoblemmus campestris and L. sylvestris

Ecology and Evolution, Volume 16, Issue 10, October 2026.
We investigated whether genomic divergence between two geographically overlapping, morphologically cryptic crickets, Loxoblemmus campestris and L. sylvestris, is broadly distributed or concentrated in particular genes and functions. Mitochondrial and nuclear data consistently supported divergence between the two lineages, while relatively few shared ...
Kazuhiro Satomura, Masakazu Saito, Atsushi Ogura   +2 more
wiley   +1 more source

Does Mother Provide? Re‐Examination of Maternal and Embryonic Microbiomes of Diploptera punctata

Ecology and Evolution, Volume 16, Issue 10, October 2026.
This figure summarizes the compositional differences in the non‐blattabacterial microbiomes of embryonic and adult females of the viviparous, Diploptera punctata. This shows the non‐negligible presence and possibly maternal sources of these bacterial taxa in developing embryos.
Brennan Jonas, Victoria Arrowsmith, Paul Ayayee   +2 more
wiley   +1 more source

High‐Quality Annotated ZZ Male Genome Assembly of Eulimnadia texana

Ecology and Evolution, Volume 16, Issue 10, October 2026.
Androdioecious crustaceans in the genus Eulimnadia have a unique sex‐determining system that allows examination of evolutionary models of early sex chromosome evolution. Although there is a high‐quality assembly of WW hermaphrodites, there is no complementary high‐quality male (ZZ) genome assembly yet for E. texana.
Chathumadavi Ediriweera, Stephen C. Weeks   +1 more
wiley   +1 more source

The Genome of an Ocean Wanderer: A High‐Quality Long‐Read Reference Genome for the Trindade Petrel (Pterodroma arminjoniana)

Ecology and Evolution, Volume 16, Issue 10, October 2026.
We present the first whole‐genome assembly for the Trindade petrel (Pterodroma arminjoniana), a wide‐ranging procellariiform seabird of conservation and eco‐evolutionary importance. These resources provide a reference‐quality genome for future studies of taxonomy and systematics, morphology, hybridisation, gene flow, population structure, conservation ...
Mariana Scain Mazzochi, Olga L. Herrera‐Trujillo, Ken Norris, Malcolm A. C. Nicoll, Paula Plaza, David A. Stewart, Maria P. Dias, Mónica C. Silva, Leandro Bugoni   +8 more
wiley   +1 more source