Polyamine metabolism is innervation responsive and involved in denervation‐induced muscle atrophy. Inhibition of polyamine metabolism attenuates muscle atrophy by restraining proteolysis and preserving MuSCs homeostasis. Denervation‐induced activation of FAP‐derived FGF7 drives premature MuSCs activation, while DFMO suppresses this paracrine cue to ...
Mingming Zhang +9 more
wiley +1 more source
Abstract In the search for life on Mars, understanding the origin of preserved organics is critical. Expected sources include exogenous delivery, endogenous synthesis, and potentially life. Environmental processing by ultraviolet (UV) irradiation can alter these organics, obscuring hallmarks of their origin. To deconvolve these effects, we conducted an
D. K. Buckner +7 more
wiley +1 more source
Genome architecture modulates 35S and 5S rDNA homogenization in Asteraceae
SUMMARY Concerted evolution is the model by which multicopy gene families are homogenized across genomes, with ribosomal DNA (rDNA) as its textbook example. However, the extent and efficiency of this process may vary depending on genomic factors. The plant family Asteraceae provides a natural comparative system to address the evolutionary dynamics of ...
Daniel Vitales +4 more
wiley +1 more source
Abundances in Damped Lyα Galaxies [PDF]
Damped Lyα galaxies provide a sample of young galaxies where chemical abundances can be derived throughout the whole universe with an accuracy comparable to that for the local universe. Despite a large spread in redshift, HI column density and metallicity, DLA galaxies show a remarkable uniformity in the elemental ratios rather suggestive of similar ...
openaire +1 more source
Metagenomic profiling of microbial communities and the resistome within Egyptian hospital wastewater and tap water. [PDF]
Radwan HM +4 more
europepmc +1 more source
Filtering for truth: high-precision taxonomic classification in nanopore shotgun metagenomics data through a KMA-based bioinformatic pipeline (KAPTAIN). [PDF]
Van Uffelen A +7 more
europepmc +1 more source
Chemical heterogeneity and mixed pollution are associated with microbial functional potential across soils in a coal mining subsidence landscape. [PDF]
Yin Y +10 more
europepmc +1 more source
<i>Prevotella</i>-dominated dysbiosis and predicted suppression of sulfur biosynthesis pathways associated with halitosis in Korean adults. [PDF]
Eom J-H +9 more
europepmc +1 more source
Metatranscriptomic Reanalysis of Alzheimer's Brains Identifies Low-Biomass Microbial Signals Including Enrichment of <i>Acinetobacter radioresistens</i>. [PDF]
Guix FX.
europepmc +1 more source
Using DIMet for Differential Analysis of Labeled Metabolomics Data: A Step-by-step Guide Showcasing the Glioblastoma Metabolism. [PDF]
Galvis J, Guyon J, Daubon T, Nikolski M.
europepmc +1 more source

