Results 51 to 60 of about 3,083,680 (250)

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

open access: yesAdvanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol   +18 more
wiley   +1 more source

The large area radio galaxy evolution spectroscopic survey (LARGESS) [PDF]

open access: yes, 2014
© 2016 The Authors. We present the Large Area Radio Galaxy Evolution Spectroscopic Survey (LARGESS), a spectroscopic catalogue of radio sources designed to include the full range of radio AGN populations out to redshift z ~ 0.8. The catalogue covers ~800
J. Ching
semanticscholar   +1 more source

Solid Harmonic Wavelet Bispectrum for Image Analysis

open access: yesAdvanced Science, EarlyView.
The Solid Harmonic Wavelet Bispectrum (SHWB), a rotation‐ and translation‐invariant descriptor that captures higher‐order (phase) correlations in signals, is introduced. Combining wavelet scattering, bispectral analysis, and group theory, SHWB achieves interpretable, data‐efficient representations and demonstrates competitive performance across texture,
Alex Brown   +3 more
wiley   +1 more source

A SIMPLE TECHNIQUE FOR PREDICTING HIGH-REDSHIFT GALAXY EVOLUTION [PDF]

open access: yes, 2014
We show that the ratio of galaxies' specific star formation rates (SSFRs) to their host halos' specific mass accretion rates (SMARs) strongly constrains how the galaxies' stellar masses, SSFRs, and host halo masses evolve over cosmic time.
P. Behroozi, J. Silk
semanticscholar   +1 more source

Cosmological evolution of galaxies [PDF]

open access: yes, 2013
I review the subject of the cosmological evolution of galaxies, including different aspects of growth in disk galaxies, by focussing on the angular momentum problem, mergers, and their by-products. I discuss the alternative to merger-driven growth -- cold accretion and related issues.
openaire   +2 more sources

Liquid Metal Nanotransformers for Drug‐Resistant Pan‐Cancer Therapy in Patient‐Derived Organoids

open access: yesAdvanced Science, EarlyView.
Pan‐cancer therapies are severely limited in drug‐resistance patients due to genetic mutations and other factors, resulting in poor therapeutic outcomes and constrained clinical benefit. Liquid metal nanotransformers, a new class of shape‐transformable nanomaterials capable of dramatic morphological changes, offer a promising physical strategy to ...
Xiaojie Yuan   +19 more
wiley   +1 more source

Secular evolution in barred galaxies [PDF]

open access: yes, 2007
A strong bar rotating within a massive halo should lose angular momentum to the halo through dynamical friction, as predicted by Weinberg. We have conducted fully self-consistent, numerical simulations of barred galaxy models with a live halo population and find that bars are indeed braked very rapidly.
Sellwood, J. A., Debattista, Victor P.
openaire   +2 more sources

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

open access: yesAdvanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi   +7 more
wiley   +1 more source

Galaxy formation in the Planck cosmology – I. Matching the observed evolution of star formation rates, colours and stellar masses [PDF]

open access: yes, 2014
We have updated the Munich galaxy formation model to the Planck first-year cosmology, while modifying the treatment of baryonic processes to reproduce recent data on the abundance and passive fractions of galaxies from z = 3 down to z = 0. Matching these
B. Henriques   +7 more
semanticscholar   +1 more source

An ATP‐Mediated Antibiotic β‐Peptide Nanofiber That Kills Multidrug‐Resistant Bacteria via a Multistage Mechanism

open access: yesAdvanced Science, EarlyView.
The 3K‐AP system forms infinite supramolecular fibrils that undergo controlled degradation into shorter fragments upon enzymatic hydrolysis. Multitechnique imaging reveals a stepwise bacteriolytic mechanism involving bacterial entrapment, disassembly into lethal constructs, and associated extracellular vesicle release, highlighting the dynamic ...
Sohini Chakraborty   +21 more
wiley   +1 more source

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