Results 171 to 180 of about 404,264 (228)

Expected value, to a point: Moral decision‐making under background uncertainty

open access: yesNoûs, EarlyView.
Abstract Expected value maximization gives plausible guidance for moral decision‐making under uncertainty in many situations. But it has unappetizing implications in ‘Pascalian’ situations involving tiny probabilities of extreme outcomes. This paper shows, first, that under realistic levels of ‘background uncertainty’ about sources of value independent
Christian Tarsney
wiley   +1 more source

BAF60/SWP73 subunits define subclasses of SWI/SNF chromatin remodelling complexes in Arabidopsis

open access: yesNew Phytologist, EarlyView.
Summary Evolutionarily conserved switch‐defective/sucrose nonfermentable (SWI/SNF) ATP‐dependent chromatin remodelling complexes (CRCs) alter nucleosome positioning and chromatin states, affecting gene expression to regulate important processes such as proper development and hormonal signalling pathways.
Sebastian P. Sacharowski   +23 more
wiley   +1 more source

Impact of Video Distraction on Anxiety During Anesthesia Induction in Pediatric Patients Premedicated With Midazolam: A Randomized Controlled Trial

open access: yesPediatric Anesthesia, EarlyView.
ABSTRACT Background Midazolam is commonly used and effective in reducing preoperative anxiety in children. Nonpharmacological interventions, such as video distraction, are also well established for alleviating preoperative anxiety in pediatric patients, particularly those treated in ambulatory settings.
Armin Sablewski   +11 more
wiley   +1 more source

Engineering Gypsophila elegans hairy root cultures to produce endosomal escape‐enhancing saponins

open access: yesPlant Biotechnology Journal, EarlyView.
Summary The limited cytosolic delivery of DNA and protein‐based therapeutics due to endosomal entrapment reduces drug efficacy, increasing treatment costs and possible side effects in human and veterinary medicine as a consequence of higher administered dosages.
Elia Lacchini   +4 more
wiley   +1 more source

A Role for the Plastidial GPT2 Translocator in the Modulation of Lignin Biosynthesis

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Engineering plants with reduced lignin content can result in pleiotropic growth defects. In stems of Arabidopsis plants with reduced expression of hydroxycinnamoyl CoA: shikimate hydroxycinnamoyl transferase (HCT), the plastidial glucose 6‐phosphate: phosphate co‐transporter GPT2 is highly overexpressed, and this coincides with reduced lignin ...
Aditi Subramani Raju   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy