Results 241 to 250 of about 536,073 (373)

Characterization of Human Senescent Cell Biomarkers for Clinical Trials

open access: yesAging Cell, EarlyView.
Assessment of T‐cell p16_variant 5 expression may be useful for selecting participants in clinical trials of senolytics. We further characterize p16_variant 5 expression in the context of senescence and demonstrate that correlated plasma senescence‐associated secretory phenotype factors could be used in lieu of the technically challenging T‐cell ...
Joshua N. Farr   +6 more
wiley   +1 more source

Persistence of Ancestral KhoeSan Mitochondrial Patterns in Contemporary South African Populations

open access: yesAnnals of Human Genetics, EarlyView.
Abstract Introduction Southern Africa has been inhabited by hunter‐gatherers for at least 20,000 years and has received diverse immigration flows in the last 2000 years. The original inhabitants have interacted with the pastoralist migrants from Eastern Africa (∼2000 ybp), followed by the southern Bantu migration arriving some 1000 ybp, and more ...
Maria Eugenia D'Amato   +7 more
wiley   +1 more source

From Brad to worse: Rule‐consequentialism and undesirable futures

open access: yesRatio, Volume 35, Issue 4, Page 275-288, December 2022., 2022
Abstract This paper asks how rule‐consequentialism might adapt to very adverse futures, and whether moderate liberal consequentialism can survive into broken futures and/or futures where humanity faces imminent extinction. The paper first recaps the recent history of rule‐consequentialist procreative ethics.
Tim Mulgan
wiley   +1 more source

Strongly lensed supernovae: lessons learned. [PDF]

open access: yesPhilos Trans A Math Phys Eng Sci
Goobar A   +2 more
europepmc   +1 more source

Has Politics Become More Professional? Career and Legislative Professionalisation in the Australian Parliament Since 1950

open access: yesAustralian Journal of Politics &History, EarlyView.
“Professional politicians” have been lamented for their perceived negative impact on representative democracy. However, the concept of “political professionalisation” is deployed inconsistently, making these claims difficult to assess. This article develops a framework to measure professionalisation across two dimensions: career professionalisation ...
Peter Ferguson   +3 more
wiley   +1 more source

A genome‐wide phylogeny and the diversification of genus Liriomyza (Diptera: Agromyzidae) inferred from anchored phylogenomics

open access: yesSystematic Entomology, Volume 48, Issue 1, Page 178-197, January 2023., 2023
Phylogenetic relationships are reconstructed among the Liriomyza leafminers using phylogenomic analysis of nuclear gene loci obtained by anchored hybrid enrichment (AHE). Trees inferred using multiple data types and analysis methods are congruent and individual clade support confirms morphological species groups and relationships among them.
Jing‐Li Xuan   +7 more
wiley   +1 more source

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