Results 171 to 180 of about 31,964 (257)

Silicosarcoidosis: Histologic and Clinical Features of an Occupational Granulomatous Disease

open access: yesAmerican Journal of Industrial Medicine, Volume 68, Issue 6, Page 491-507, June 2025.
ABSTRACT Sarcoidosis is a multisystem inflammatory disease of unknown etiology. Growing evidence indicates that occupational exposure to respirable crystalline silica (RCS) is associated with an increased incidence of sarcoidosis. Yet a diagnosis of sarcoidosis rarely prompts investigation to identify preventable exposures.
Jeremy T. Hua   +11 more
wiley   +1 more source

Integrative cross‐tissue analysis unveils complement‐immunoglobulin augmentation and dysbiosis‐related fatty acid metabolic remodeling during mammalian aging

open access: yesiMeta, Volume 4, Issue 3, June 2025.
Our study provides a comprehensive multi‐omics profile of aging, integrating proteomic, metabolomic, and metagenomic analyses across diverse tissues and plasma. We identified the synergistic amplification of the circulating complement system and tissue‐wide immunoglobulin accumulation as key molecular drivers of inflammaging.
Feng Zhang   +17 more
wiley   +1 more source

Synchrotron intensity gradient revealing magnetic fields in galaxy clusters. [PDF]

open access: yesNat Commun
Hu Y   +5 more
europepmc   +1 more source

The microbiologist's guide to metaproteomics

open access: yesiMeta, Volume 4, Issue 3, June 2025.
Metaproteomics within the multi‐omics framework provides a comprehensive view of microbial systems by identifying proteins, quantifying their levels, detecting posttranslational modifications (PTMs), mapping protein–protein interactions (PPIs), and localizing proteins.
Tim Van Den Bossche   +31 more
wiley   +1 more source

How Moral Appraisals Function in Sticky Crises: Theorizing Within the Triadic Appraisal Framework of Situational Crisis Communication Theory

open access: yesJournal of Contingencies and Crisis Management, Volume 33, Issue 2, June 2025.
ABSTRACT This framework advocates for theory‐driven research on moral outrage‐inducing sticky crises, aiming to clarify three key areas: (1) how the three preventable crisis clusters (i.e., human‐error, management misconduct and scansis) and information‐giving strategies (i.e., instructing and adjusting information) shape stakeholders' perceptions of ...
Rongting Niu   +3 more
wiley   +1 more source

Antibiotic‐induced decrease of bacterial load in guinea pig intestine reduces α2‐adrenoceptor expression and activity in peristaltic motor inhibition

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 12, Page 2642-2661, June 2025.
Background and Purpose The use of analgosedatives in critically ill patients carries the risk of impairing gastrointestinal (GI) propulsion and could thereby lead to sepsis. The gut microbiota can influence GI motility, but whether GI microbial dysbiosis modifies GI peristalsis impairment by analgosedative drugs has not yet been analysed. This question
Aitak Farzi   +5 more
wiley   +1 more source

Repeated Low‐Level Inflammatory Challenge Leads to Alterations in the TNF‐CXCL10 Signalling Pathway in Mouse Cerebral Endothelial Cells In Vitro

open access: yesJournal of Neurochemistry, Volume 169, Issue 6, June 2025.
Intermittent, mild pro‐inflammatory systemic disease contributes to cerebrovascular pathology, however the mechanism of low‐level exposure causing injury remains unclear. Our RNA‐Seq analysis reveals continuous activation of tumour necrosis factor (TNF)‐Nuclear Factor kappa B (NF‐κB) signalling and multiple downstream inflammatory mediators in mouse ...
Megan Ritson   +3 more
wiley   +1 more source

Unique starch biosynthesis pathways in wild rice revealed by multi‐omics analyses

open access: yesPlant Biotechnology Journal, Volume 23, Issue 6, Page 2429-2445, June 2025.
Summary Australian wild rice species (AWS) possess unique starch properties characterized by a slow digestibility rate. However, the genomic and transcriptomic variations of starch‐synthesis‐related genes (SSRGs) influencing starch physiochemical properties in AWS remain unclear.
Nurmansyah   +3 more
wiley   +1 more source

Abstracts

open access: yesMolecular Oncology, Volume 19, Issue S1, Page 1-895, June 2025.
Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

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