Results 151 to 160 of about 24,501 (297)

Sensitization of Non‐M3 Acute Myeloid Leukemia Blasts to All‐Trans Retinoic Acid by the LSD1 Inhibitor Tranylcypromine: TRANSATRA Phase I Study

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT The treatment of elderly, nonfit acute myeloid leukemia (AML)/MDS patients with relapsed/refractory (R/R) disease remains challenging. As histone demethylase LSD1 (KDM1A) is a rational therapeutic target in AML, we conducted a phase I trial (“rolling‐six design”) with the LSD1 inhibitor tranylcypromine (TCP, dose levels [DL] 20, 40, 60, 80 mg ...
Michael Kruszewski   +22 more
wiley   +1 more source

Impact of the Cosmic Web on the Properties of Galaxies in IllustrisTNG Simulations

open access: yesThe Astrophysical Journal
We investigate the influence of the cosmic web on galaxy properties in the IllustrisTNG simulations. To disentangle the effects of galaxy groups and cosmic filaments, we divide the cosmic web environment into four categories: group, group-dominated ...
Guangyao Yu   +5 more
doaj   +1 more source

Factors affecting the mean electrical axis of the heart in trained Thoroughbreds

open access: yesEquine Veterinary Education, EarlyView.
Summary Background Assuming that the ventricular myocardium of horses is subjected to exercise‐induced hypertrophy, we hypothesised that the mean electrical axis (MEA) of the heart would change. Objectives To define a longitudinal study to detect any changes in the direction of the MEA in Thoroughbred horses using ECG.
M. Felici   +6 more
wiley   +1 more source

Nuclear Activity of Galaxies within Groups [PDF]

open access: bronze, 1987
K. J. Fricke, W. Kollatschny
openalex   +1 more source

Feasibility of Remote Intensive Monitoring: A Novel Approach to Reduce Black Postpartum Maternal Cardiovascular Complications

open access: yesJournal of Midwifery &Women's Health, EarlyView.
Introduction Approximately 53% of maternal mortality occurs in the postpartum period, a time with little monitoring and health surveillance. The objective of this study was to test the feasibility, usability, appropriateness, and acceptability of remote low‐burden physiologic monitoring of Black postpartum women, using a novel soft wearable patch and ...
Michelle Villegas‐Downs   +10 more
wiley   +1 more source

Groups of galaxies [PDF]

open access: yesProceedings of Baryons in Dark Matter Halos — PoS(BDMH2004), 2004
openaire   +2 more sources

Effectiveness of Virtual Reality Interventions for Perioperative Anxiety in Adults: A Systemic Review With Meta‐Analysis

open access: yesJournal of Clinical Nursing, EarlyView.
ABSTRACT Background Surgery often causes anxiety in adults due to various factors, including fear of anaesthesia and loss of independence. This anxiety can lead to higher anaesthesia requirements and more postoperative complications. Virtual Reality (VR) is increasingly used as a non‐pharmacological intervention to decrease perioperative anxiety.
Salihah Asiri   +3 more
wiley   +1 more source

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