Results 171 to 180 of about 2,756,668 (275)

Revolutionizing multi‐omics analysis with artificial intelligence and data processing

open access: yesQuantitative Biology, Volume 13, Issue 3, September 2025.
Abstract Our understanding of intricate biological systems has been completely transformed by the development of multi‐omics approaches, which entail the simultaneous study of several different molecular data types. However, there are many obstacles to overcome when analyzing multi‐omics data, including the requirement for sophisticated data processing
Ali Yetgin
wiley   +1 more source

Human γδ T Cell Function Is Impaired Upon Mevalonate Pathway Inhibition

open access: yesImmunology, Volume 175, Issue 3, Page 300-322, July 2025.
Mevalonate pathway is important for the effector function of gammadelta T cells. Inhibition of the pathway in vivo and in vitro impairs cytokine and cytotoxic molecule production by mainly affecting protein prenylation and disturbing intracellular signalling in Vdelta2 T cells. Created with Biorender.
Tsz Kin Suen   +14 more
wiley   +1 more source

Light Quantity Impacts Early Response to Cold and Cold Acclimation in Young Leaves of Arabidopsis

open access: yesPlant, Cell &Environment, Volume 48, Issue 7, Page 5030-5052, July 2025.
ABSTRACT Plant reactions to stress vary with development stage and fitness. This study assessed the relationship between light and chilling stress in Arabidopsis acclimation. By analysing the transcriptome and proteome responses of expanding leaves subjected to varying light intensity and cold, 2251 and 2064 early response genes and proteins were ...
Markéta Luklová   +14 more
wiley   +1 more source

Exploiting Machine Learning and Disequilibrium in Galaxy Clusters to Obtain a Mass Profile

open access: yesThe Astrophysical Journal Letters
We use 3D k -means clustering to characterize galaxy substructure in the A2146 cluster of galaxies ( z = 0.2343). This method objectively characterizes the cluster’s substructure using projected position and velocity data for 67 galaxies within a 2.305 ...
Mark J. Henriksen, Prajwal Panda
doaj   +1 more source

Stealing galaxies from galaxy clusters [PDF]

open access: yesarXiv
We investigate galaxy groups that reside in the field but have been previously processed by galaxy clusters. Observationally, they would appear to have the same properties as regular field groups at first glance. However, one would expect to find quantifiable differences in processed groups as dynamical interactions within clusters perturb them. We use
arxiv  

Integrative cross‐tissue analysis unveils complement‐immunoglobulin augmentation and dysbiosis‐related fatty acid metabolic remodeling during mammalian aging

open access: yesiMeta, Volume 4, Issue 3, June 2025.
Our study provides a comprehensive multi‐omics profile of aging, integrating proteomic, metabolomic, and metagenomic analyses across diverse tissues and plasma. We identified the synergistic amplification of the circulating complement system and tissue‐wide immunoglobulin accumulation as key molecular drivers of inflammaging.
Feng Zhang   +17 more
wiley   +1 more source

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