Results 211 to 220 of about 373,823 (371)

Has Politics Become More Professional? Career and Legislative Professionalisation in the Australian Parliament Since 1950

open access: yesAustralian Journal of Politics &History, EarlyView.
“Professional politicians” have been lamented for their perceived negative impact on representative democracy. However, the concept of “political professionalisation” is deployed inconsistently, making these claims difficult to assess. This article develops a framework to measure professionalisation across two dimensions: career professionalisation ...
Peter Ferguson   +3 more
wiley   +1 more source

Epithelial Memory After Respiratory Viral Infection in Mice Results in Prolonged Enhancement of Antigen Presentation

open access: yesAllergy, EarlyView.
RSV infection induces lasting epigenetic and transcriptional changes in LECs, upregulating MHC‐I and MHC‐II, further amplified by LPS exposure. This is accompanied by increased antigen uptake, processing, and presentation. These persistent alterations may influence immune responses, potentially impacting both immunity to infection and respiratory ...
Piotr P. Janas   +11 more
wiley   +1 more source

Truncations in the X-Ray Halos of Early-type Galaxies as a Tracer of Feedback and Mergers

open access: yesThe Astrophysical Journal
The morphology of X-ray halos in early-type galaxies depends on key structure assembly processes, such as feedback and mergers. However, the signatures of these processes are difficult to characterize due to their faint and amorphous nature.
Nushkia Chamba   +4 more
doaj   +1 more source

CTCF Is Essential for the Development and Maintenance of CALM‐AF10‐Induced Leukemia

open access: yesCancer Science, EarlyView.
CTCF regulates TGM2 gene expression by modulating key histone modifications, including increased acetylation of H3K27 (H3K27ac) and trimethylation of H3K4 (H3K4me3), along with decreased trimethylation of H3K27 (H3K27me3). These epigenetic changes are critical for maintaining the stem‐like properties of CALM‐AF10‐induced AML. Pharmacological inhibition
Yoko Kuroki   +5 more
wiley   +1 more source

Evidence for a Redshifted Excess in the Intracluster Light Fractions of Merging Clusters at z ∼ 0.8

open access: yesThe Astrophysical Journal Letters
The intracluster light (ICL) fraction is a well-known indicator of the dynamical activity in intermediate-redshift clusters. Merging clusters in the redshift interval 0.18 < z < 0.56 have a distinctive peak in the ICL fractions measured between ∼3800 and
Yolanda Jiménez-Teja   +3 more
doaj   +1 more source

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