Results 351 to 360 of about 12,590,287 (391)

Empowering bioinformatics communities with Nextflow and nf-core. [PDF]

open access: yesGenome Biol
Langer BE   +43 more
europepmc   +1 more source

Sensitization of Non‐M3 Acute Myeloid Leukemia Blasts to All‐Trans Retinoic Acid by the LSD1 Inhibitor Tranylcypromine: TRANSATRA Phase I Study

open access: yesEuropean Journal of Haematology, Volume 115, Issue 3, Page 266-277, September 2025.
ABSTRACT The treatment of elderly, nonfit acute myeloid leukemia (AML)/MDS patients with relapsed/refractory (R/R) disease remains challenging. As histone demethylase LSD1 (KDM1A) is a rational therapeutic target in AML, we conducted a phase I trial (“rolling‐six design”) with the LSD1 inhibitor tranylcypromine (TCP, dose levels [DL] 20, 40, 60, 80 mg ...
Michael Kruszewski   +22 more
wiley   +1 more source

Characterizing the structural variations in the genome of the mandarin variety, IrM2, induced by gamma irradiation

open access: yesPlant Biotechnology Journal, Volume 23, Issue 9, Page 3814-3823, September 2025.
Summary Fruits with few or no seeds are favoured by consumers because they provide an improved eating experience alongside other important quality traits such as taste and shelf‐life. Gamma irradiation has been widely used to induce favourable trait changes in plants, including a reduction in seediness.
Upuli Nakandala   +5 more
wiley   +1 more source

Galaxy as a gateway to bioinformatics: Multi-Interface Galaxy Hands-on Training Suite (MIGHTS) for scRNA-seq. [PDF]

open access: yesGigascience
Goclowski CL   +13 more
europepmc   +1 more source

Choosing the right crowdsourcing strategy: Implications for governments' crowdsourcing initiatives

open access: yesPublic Administration Review, Volume 85, Issue 5, Page 1302-1315, September/October 2025.
Abstract Building on recent advances in crowdsourcing research, we argue that, when using crowdsourcing, governments should accurately select the crowd they wish to engage with, depending on the problem to be solved. While targeting a large crowd may be common, it is not always the most appropriate: it can waste significant resources without ...
Ana Colovic   +2 more
wiley   +1 more source

Galaxy Helm chart: a standardized method for deploying production Galaxy servers. [PDF]

open access: yesBioinformatics
Goonasekera N   +3 more
europepmc   +1 more source

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