Results 291 to 300 of about 4,466,693 (321)
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Drug development research (Print), 2021
As an anti‐tumor agent, histone deacetylases (HDACs) inhibitors have attracted wide attention. ACY1215 is a highly effective selective inhibitor of HDAC6, which can inhibit many kinds of tumors.
Y. Ruan, Luoluo Wang, Yeting Lu
semanticscholar +1 more source
As an anti‐tumor agent, histone deacetylases (HDACs) inhibitors have attracted wide attention. ACY1215 is a highly effective selective inhibitor of HDAC6, which can inhibit many kinds of tumors.
Y. Ruan, Luoluo Wang, Yeting Lu
semanticscholar +1 more source
The American Journal of Surgery, 2008
Gallbladder cancer (GC) is a relatively rare but highly lethal neoplasm. We review the epidemiology, etiology, pathology, symptoms, diagnosis, staging, treatment, and prognosis of GC.A Pubmed database search between 1971 and February 2007 was performed. All abstracts were reviewed and articles with GC obtained; further references were extracted by hand-
Stavros, Gourgiotis +5 more
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Gallbladder cancer (GC) is a relatively rare but highly lethal neoplasm. We review the epidemiology, etiology, pathology, symptoms, diagnosis, staging, treatment, and prognosis of GC.A Pubmed database search between 1971 and February 2007 was performed. All abstracts were reviewed and articles with GC obtained; further references were extracted by hand-
Stavros, Gourgiotis +5 more
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Southern Medical Journal, 1990
We have reported a case of primary carcinoma of the gallbladder and reviewed 42 other cases seen at the Marshall University School of Medicine affiliated hospitals over the last 27 years. Most of the patients were female (74.5%) and elderly (mean age 66.9 years), and had metastatic or locally invasive disease (79%); 95% had adenocarcinoma. Preoperative
Wheeler We, Friedman
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We have reported a case of primary carcinoma of the gallbladder and reviewed 42 other cases seen at the Marshall University School of Medicine affiliated hospitals over the last 27 years. Most of the patients were female (74.5%) and elderly (mean age 66.9 years), and had metastatic or locally invasive disease (79%); 95% had adenocarcinoma. Preoperative
Wheeler We, Friedman
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Amyloidosis of the gallbladder mimicking gallbladder cancer [PDF]
Journal of Gastroenterology, 2007 We report a rare case of amyloidosis of the gallbladder in a 63-year-old woman with a history of primary amyloidosis. The patient was asymptomatic. Blood chemistry and hematologic laboratory levels, as well as values for tumor markers, were unremarkable. Ultrasonography (US) of the abdomen showed a focal echogenic lesion (22 x 15 mm) in the body of the
Hitoshi Yamada +4 more
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Surgical Clinics of North America, 2014
Gallbladder cancer remains a relatively rare malignancy with a highly variable presentation. Gallbladder cancer is the most common biliary tract malignancy with the worst overall prognosis. With the advent of the laparoscope, in comparison with historical controls, this disease is now more commonly diagnosed incidentally and at an earlier stage ...
Jessica A, Wernberg, Dustin D, Lucarelli
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Gallbladder cancer remains a relatively rare malignancy with a highly variable presentation. Gallbladder cancer is the most common biliary tract malignancy with the worst overall prognosis. With the advent of the laparoscope, in comparison with historical controls, this disease is now more commonly diagnosed incidentally and at an earlier stage ...
Jessica A, Wernberg, Dustin D, Lucarelli
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Gallbladder Wall Calcification and Gallbladder Cancer
Journal of the American College of Surgeons, 2013and may have indicated a fundamental difference inapproach of some surgeons undertaking OPD.We do share the authors’ views on LPD and believe itdoes have an important role to play in the management ofperiampullary carcinomas. However, before its wide-spread adoption to clinical practice, we feel a multicenterrandomize controlled trial of LPD vs OCD for
Stephanie M. Wong, Issie S. Weissglas
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Journal of the American College of Surgeons, 2002
The majority of patients with gallbladder cancer (GBC) have advanced disease at the time of diagnosis and are unresectable. Longterm survival is usually seen in a subset of patients with early GBC (EGBC)-cancer confined to the mucosa (pT1a) and muscularis (pT1b). Management guidelines of EGBC are not yet defined and are controversial.
Narendra Krishnani +6 more
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The majority of patients with gallbladder cancer (GBC) have advanced disease at the time of diagnosis and are unresectable. Longterm survival is usually seen in a subset of patients with early GBC (EGBC)-cancer confined to the mucosa (pT1a) and muscularis (pT1b). Management guidelines of EGBC are not yet defined and are controversial.
Narendra Krishnani +6 more
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Seminars in Surgical Oncology, 2000
Gallbladder cancer has a reputation for being aggressive and incurable. Single institution series, however, have defined successful management strategies in which the extent of resection is based on the stage of the tumor at presentation. Careful ultrasound screening for abnormalities in the gallbladder wall, and CA19-9 serum determination prior to ...
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Gallbladder cancer has a reputation for being aggressive and incurable. Single institution series, however, have defined successful management strategies in which the extent of resection is based on the stage of the tumor at presentation. Careful ultrasound screening for abnormalities in the gallbladder wall, and CA19-9 serum determination prior to ...
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Chemoradiotherapy in gallbladder cancer
Journal of Surgical Oncology, 2006AbstractGallbladder cancer (GC) is considered a rare disease associated with a poor prognosis. Unfortunately, the low number of cases makes the performance of trials addressing the role of adjuvant, neoadjuvant, and/or palliative therapy difficult. For a long time, the majority of trials were 5‐fluorouracil (5 FU)‐based, and results were uniformly poor.
Andres Cordova +10 more
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Management of Gallbladder Cancer
Gastroenterology Clinics of North America, 2010Resection is a means of improving survival in patients with gallbladder cancer. A more aggressive surgical approach, including resection of the gallbladder, liver, and regional lymph nodes, is advisable for patients with T1b to T4 tumors. Aggressive resection is necessary because a patient's gallbladder cancer stage determines the outcome, not the ...
Shiva Jayaraman, William R. Jarnagin
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