Results 171 to 180 of about 62,243 (240)

Prognostic comparison between implantable cardioverter‐defibrillator and amiodarone in cancer patients

open access: yesJournal of Arrhythmia, Volume 41, Issue 3, June 2025.
The effectiveness of implantable cardioverter‐defibrillator (ICD) versus amiodarone in cancer patients remains unclear. Using 2010–2015 cancer registry data from 36 hospitals in Osaka, Japan, we found that ICD significantly improves cancer patients' prognosis compared to amiodarone.
Hirota Kida   +6 more
wiley   +1 more source

A cross‐tissue transcriptome‐wide association study identifies novel susceptibility genes for atrial fibrillation

open access: yesJournal of Arrhythmia, Volume 41, Issue 3, June 2025.
This cross‐tissue transcriptome‐wide association study identified five novel AF susceptibility genes (CAMK2D, SPAST2L, CEP68, FKBP7, and SHRMOO3). Elevated expression of FKBP7, CEP68, and CAMK2D increases AF risk, while SPATS2L shows a protective effect, with colocalization analysis implicating CEP68 and SPATS2L as prioritized candidates.
Yalin Yuan   +4 more
wiley   +1 more source

Clinical Use of Comprehensive Genomic Profiling Tests in Intrahepatic Cholangiocarcinoma: A Single‐Center Retrospective Study

open access: yesLiver International Communications, Volume 6, Issue 2, June 2025.
ABSTRACT The clinical utility of comprehensive genomic profiling (CGP) in intrahepatic cholangiocarcinoma (ICC) remains to be fully elucidated. This study analysed CGP test results and evaluated treatment outcomes with fibroblast growth factor receptor (FGFR) inhibitors in patients with ICC, aiming to assess their efficacy in cases with specific FGFR ...
Makiko Urabe   +10 more
wiley   +1 more source

Detection of Gallbladder Disease Types Using a Feature Engineering-Based Developed CBIR System. [PDF]

open access: yesDiagnostics (Basel)
Bozdag A   +5 more
europepmc   +1 more source

SOAT1 Activates NLRP3 Inflammasome to Promote Cancer‐Related Lymphangiogenesis and Metastasis via IL‐1β/IL‐1R‐1 Axis in Oral Squamous Cell Carcinoma

open access: yesMolecular Carcinogenesis, Volume 64, Issue 6, Page 1039-1056, June 2025.
ABSTRACT Oral squamous cell carcinoma (OSCC) is a prevalent type of cancer in the head and neck region, significantly impacting patient survival rates and quality of life. Lymph node (LN) metastasis is a lead contributor to the poor prognosis associated with OSCC.
Chengzhi Zhao   +6 more
wiley   +1 more source

The Long Noncoding RNA LINC02820 Promotes Tumor Growth and Metastasis Through Regulating MYH9 Expression in Esophageal Squamous Cell Carcinoma

open access: yesMedComm, Volume 6, Issue 6, June 2025.
This study demonstrates that the RNA‐binding protein IGF2BP2 binds to and stabilizes LINC02820, leading to elevated LINC02820 expression in esophageal squamous cell carcinoma (ESCC). Moreover, association of LINC02820 with MYH9 protein protects MYH9 from proteasomal degradation, thus upregulating MYH9 to promote tumor growth and metastasis in ESCC ...
Xiaomin Xu   +8 more
wiley   +1 more source

Transplantation of the human liver [PDF]

open access: yes, 1985
Iwatsuki, S, Shaw, BW, Starzl, TE
core  

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