Results 51 to 60 of about 56,531 (280)

The Development and Pilot Clinical Study of CD147 Targeted Antagonistic Peptide Probe for Tumor Imaging

Advanced Science, EarlyView.
This study establishes [68Ga]Ga‐DOTA‐AP9 as a first‐in‐human CD147‐targeted PET tracer with favorable safety and specific tumor uptake. Tracer accumulation correlates with CD147 expression in patients, enabling noninvasive quantification of CD147‐positive malignancies.
Xiaokun Ma, Rui Guo, Dongfeng Niu, Yufei Song, Zhenyao Zhang, Xiangxi Meng, Lili Mao, Haifeng Huang, Hua Zhu, Zhi Yang, Teli Liu   +10 more
wiley   +1 more source

Melatonin Alleviates Graft Biliary Fibrosis by Inhibiting VIM+ Cholangiocyte Subcluster via Hypoxia/TGF‐β‐CREM‐VIM Axis

Advanced Science, EarlyView.
Single‐cell RNA sequencing verified the presence of the VIM+ biliary epithelial cell (BEC) in the bile ducts of NAS patients. The hypoxia/TGF‐β‐CREM‐VIM axis mediated phenotypic switch toward VIM+ BEC is validated using a hypoxia/TGF‐β‐stimulated cellular model, a rat liver transplantation model, BEC‐specific Crem conditional knockout rats, and BEC ...
Zhaoyi Wu, Nengsheng Fu, Zhongxin Huang, Yu Mou, Ensi Ma, Xiaoshi Wang, Tian Dong, Yujun Zhang, Danqing Liu, Di Jiang, Jingya Kuang, Rui Liao, Yifeng Tao, Leida Zhang, Chengcheng Zhang   +14 more
wiley   +1 more source

БИЛИАРНАЯ ПАТОЛОГИЯ И ЕЕ КЛИНИЧЕСКИЕ «МАСКИ». Часть 1

Архивъ внутренней медицины, 2012
The article gives systematicaly organized literature data and the author’s observations of different biliar tract disorder variants. The focus is on the comorbidity formation mechanisms analysis and the difficulties in differential diagnostics of various
Е. Ю. Еремина
doaj   +1 more source

Short‐Term Outcomes and Cost Drivers of Emergency Surgery for Acute Abdominal Disease in Super‐Elderly Patients: A Study in the Japanese Tertiary Care Hospital

Annals of Gastroenterological Surgery, EarlyView.
This retrospective study analyzed patients aged ≥ 85 years undergoing emergency abdominal surgery, focusing on short‐term outcomes and inpatient cost structure under the Japanese DPC system. Although major complications occurred in 19.4% of patients, more than 70% were discharged home.
Yuta Kobayashi, Ryo Oikawa, Yumi Shibuya, Masakazu Tatsuno, Atsuya Kamiyama, Tsuyoshi Ozawa, Keiichiro Hara, Shojiro Hata, Hirokazu Yamaguchi   +8 more
wiley   +1 more source

Gallbladder schistosomiasis

Autopsy and Case Reports
Schistosomiasis is an infectious disease caused by parasitic flatworms of the genus Schistosoma. The species Schistosoma mansoni is associated with hepatosplenic disease.
Gabriela Del Angel-Millán, José Jukemura, Júlia Bragion Bicudo, Ricardo Jureidini, André Luís Montagnini, Vanderlei Segatelli, Thiago Costa Ribeiro, Guilherme Naccache Namur, Thiago Nogueira Costa, Lucas Cata Preta Stolzemburg, Emilio Elias Abdo, Ulysses Ribeiro Júnior, Paulo Herman, Estela Regina Ramos Figueira   +13 more
doaj   +1 more source

Dietary N-3 polyunsaturated fatty acids decrease biliary cholesterol saturation in gallstone disease [PDF]

, 1992
Because fatty acid composition of biliary phospholipids influences cholesterol secretion into bile, we investigated whether replacement of n-1 monounsaturated or n-6 polyunsaturated fatty acids with n-3 polyunsaturated fatty acids in biliary ...
Sven Fischer, Seifferth, Bernd, Paumgartner, Gustav, Holl, Joseph, Frieder Berr, Werner Richter, Joseph Holl, Bernd Seifferth, Jüngst, Dieter, Dieter Jongst, Berr, Frieder, Richter, Werner O., Fischer, Sven, Gustav Paumgartner   +13 more
core   +1 more source

Pylorus‐Preserving Gastrectomy for Gastric Cancer: Current Evidence and Future Directions

Annals of Gastroenterological Surgery, EarlyView.
This review aims to outline the current evidence and future directions of PPG, focusing on the feasibility of extending its application beyond its traditional indications. ABSTRACT Pylorus‐preserving gastrectomy (PPG) is a function‐preserving surgery for clinically T1N0M0 (cT1N0M0) early gastric cancer (EGC) located in the middle third of the stomach ...
Sa‐Hong Kim, Hyuk‐Joon Lee
wiley   +1 more source

Epidemiology and Burden of Gallbladder and Biliary Diseases and the Socioeconomic Factors in the Region of Middle East and North Africa, 1990–2021: Estimates From the Global Burden of Disease 2021 Study

Health Science Reports
Background and Aims As common disorders affecting the digestive system, gallbladder and biliary diseases present a significant health issue. This research aimed to assess the burden of these conditions in the Middle East and North Africa (MENA) region ...
Zahra Isari, Melika Azizi Ghiasabadi, Mohammad Amin Gharihe, Amir Mashayekhi, Ali Khashaveh, Esmaeil Dabiri, Saeed Bahrampour, Arman Farsi, Kamiar Izadpanah, Hossein Pourghadamyari, Hamid Sharifi, Omid Eslami, Seyed Aria Nejadghaderi   +12 more
doaj   +1 more source

Clinically Relevant Bleeding in Individuals With Cancer: Insights From a Nationwide Cohort Study

American Journal of Hematology, EarlyView.
ABSTRACT Cancer care is often complicated by coagulopathy leading to thrombosis and bleeding. While venous thromboembolism (VTE) has been extensively studied, bleeding remains an underestimated threat. To address this knowledge gap, we leveraged the Epic Cosmos database to determine the impact of cancer‐associated clinically relevant bleeding (CRB) in ...
Ming Y. Lim, Radhika Gangaraju, Omid Jafari, Zihan Yang, Joyce W. T. Tiong, Elizabeth C. L. Chiang, Shengling Ma, Jun Y. Jiang, Justine Ryu, Barbara D. Lam, Mrinal Ranjan, Ang Li   +11 more
wiley   +1 more source

Table_1_The increasing incidence and high body mass index-related burden of gallbladder and biliary diseases–A results from global burden of disease study 2019.pdf

, 2022
BackgroundGallbladder and biliary diseases are common gastrointestinal conditions associated with huge socioeconomic costs and are considered risk factors for cardiovascular diseases and digestive system cancers.
Juanjuan Qin (9546703), Xiaojing Zhang (163406), Ming Zhuo (6618326), Fang Lei (42063), Yi Li (1144), Shuhua Liu (1598038), Weifang Liu (6194423), Jingjing Cai (604345), Maolin Yi (14206595), Lijin Lin (671929), Yanxiao Ji (11842208), Hongliang Li (122229), Peng Zhang (2071), Junming Ye (12650139), Xuewei Huang (3753586)   +14 more
core   +1 more source