Results 221 to 230 of about 43,472 (345)

Pharmacokinetics and Safety of Single‐Dose Apraglutide in Individuals with Normal and Impaired Hepatic Function: A Phase 1, Open‐Label Trial

Clinical Pharmacology in Drug Development, Volume 15, Issue 1, January 2026.
Abstract Intestinal failure‐associated liver disease occurs in 20% to 30% of patients with short bowel syndrome and intestinal failure (SBS‐IF). Apraglutide is a glucagon‐like peptide‐2 (GLP‐2) analog in clinical development for the treatment of patients with SBS‐IF.
Gerard Greig, Justin Hay, Patricia Valencia, Mena Boules, Tomasz Masior   +4 more
wiley   +1 more source

Gallbladder adenosquamous carcinoma: a case report and a review of the role of laparoscopy in managing a rare entity. [PDF]

J Surg Case Rep
Yafee H, Rudnicki Y, Tal S, Lifshitz G, Avital S, Lahav L.   +5 more
europepmc   +1 more source

Synthetic lethality in cancer therapy: Mechanisms, models and clinical translation for overcoming therapeutic resistance

Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.
Application of synthetic lethality screening in drug resistance models. Abstract Background and Rationale Synthetic lethality (SL)‐based strategies hold significant promise for overcoming therapeutic resistance, a critical bottleneck in cancer treatment where cancer cells evade anticancer therapies, leading to diminished efficacy or treatment failure ...
Junyan Li, Liyuan Zhang, Yan Shang, Juan Liu, Hailong Zhao   +4 more
wiley   +1 more source

Bile metabolite palmitic acid augments the migration of gallbladder cancer cells through the ROS/NF-кB signaling pathway. [PDF]

Sci Rep
Da X, Guo Q, Lu Y, Huang J, Mo J, Lu L, Fan M, Zhao X, Guo T, Qi Z, Haoshang, Lu H.   +11 more
europepmc   +1 more source

Tirzepatide and Cardiovascular Outcomes: A Narrative Review of Mechanisms, Efficacy and Implications for Heart Failure Management

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 1, January 2026.
Integrated framework for tirzepatide in HFpEF management. Through metabolic, haemodynamic, structural and anti‐inflammatory pathways, tirzepatide modifies the disease trajectory of HFpEF, leading to improvements in symptoms, functional capacity and reduction in HF events.
Hamza A. Abdul‐Hafez, Ameer Awashra, Sosana Bdir, Sarah Saife, Qasem Salah, Mohammed Barbarawi, Thabet Swaileh, Ahmed Emara, Mohamed S. Elgendy, Abdalhakim Shubietah   +9 more
wiley   +1 more source

Identification of Cumulative Assessment Groups of Pesticides [PDF]

, 2012
Boberg, Julie, Bredsdorff, Lea, Hadrup, Niels, Isling, Louise Krag, Kroghsbo, Stine, Larsen, John Christian, Mortensen, Alicja, Nielsen, Elsa, Nørhede, Pia   +8 more
core   +1 more source

Global, regional, and national burden of gallbladder and biliary tract diseases: A systematic analysis of prevalence, incidence, deaths, and disability-adjusted life years with projections to 2050. [PDF]

Ann Hepatobiliary Pancreat Surg
Zheng Y, Duan Y, He X, Luo H, Zheng X.
europepmc   +1 more source

Comprehensive Review on the Occurrence of Aflatoxin M1 in Milk, Prevalent Health Issues Associated With It, and Innovative Strategies for Mitigation of Aflatoxin M1 in Processed Milk

Food Safety and Health, Volume 4, Issue 1, Page 67-81, January 2026.
Aflatoxins, carcinogenic compounds in milk; reduction strategies such as thermal deactivation, UV light exposure, ionizing radiation, and solvent extraction. ABSTRACT Aflatoxins (AFs) are known to be cancer causing substances recognized within milk along with the milk goods.
Akshay Ramani, Tanmay Hazra, Anamika Das, Subhadip Manik, Ayon Tarafdar, Swarnima Dey, Umesh Singh   +6 more
wiley   +1 more source

Case Report: Primary leiomyosarcoma of the canine gallbladder with intraoperative indocyanine green near-infrared fluorescence imaging. [PDF]

Front Vet Sci
Yun J, Kim Y, Park KM, Lee S.
europepmc   +1 more source

Biological Activities, Health Benefits and Synthesis of Equol and Its Derivatives: A Comprehensive Review

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
Biological activities, health benefits and structures of equol and its derivatives. ABSTRACT Equol is a metabolite transformed from daidzein by intestinal microorganisms and has received extensive attention due to its various pharmacological activities and therapeutic potential.
Jiao‐Jiao Zhuo, Bing‐Juan Li, Meng‐Ran Tian   +2 more
wiley   +1 more source