Results 41 to 50 of about 5,415,752 (133)

Peptide binding at the gasdermin D exosite reveals the structural basis for targeting the site

Acta Crystallographica Section D, Volume 82, Issue 6, Page 615-625, June 2026.
We describe the first structure of gasdermin D with a putative caspase inhibitor peptide analog at 1.6 Å resolution. This work suggests potential druggability of gasdermin D at the exosite by leveraging structure‐based computational design with biochemical characterization.Gasdermin D (GSDMD) has been identified as a critical component of the ...
Renjing Wang, Thu Ho, Aimie Ogawa, Kartika Widjaja, Zachary Brown, Song Yang, Pei Huo, Michael C. Gregory, Aman Singh, Senthil Perumal, Songnian Lin, Alan C. Cheng, Lindsay S. Garrenton, James Mu, Anthony Ogawa, Jill E. Chrencik   +15 more
wiley   +1 more source

Species‐Specific Optimisation and Environmental Regulation of Biofilm Formation in Enterobacter cloacae: Inhibitory Role of Glucose in Biofilm Development

Environmental Microbiology Reports, Volume 18, Issue 3, June 2026.
This study demonstrates that mild salinity stress (1%–2% NaCl) significantly enhances biofilm formation in Enterobacter cloacae. Using a standardised 96‐well microtiter plate assay, we optimised in vitro biofilm quantification and classification, providing a reproducible framework for studying environmental and clinical biofilm development mechanisms ...
Srishti Singh, Virendra Bahadur Yadav, Alok Kumar Singh, Gopal Nath, Sasmita Chand, Nirmalendu Sekhar Mishra, Jagdeep Kumar Nayak   +6 more
wiley   +1 more source

Bioengineered 3D hPSC‐Cholangiocyte Ducts With Physiological Signals for Biliary Disease Modeling

Advanced Healthcare Materials, Volume 15, Issue 20, 27 May 2026.
Tian and colleagues generated a bioengineered bile duct from human pluripotent stem cell (hPSC)‐derived intrahepatic cholangiocytes within a high‐throughput, 384‐well platform to systematically examine the influence of biliary physiological signals including fluid flow, stromal cells and bile acids, and models intrahepatic biliary disease progression ...
Britney Tian, Mina Ogawa, Manami Kondo, Gabrielle Langeveld, Ling Jun Huan, Feng Zhang, Andrew Hollinger, Sara Deir, Christine Bear, Boyang Zhang, Shinichiro Ogawa   +10 more
wiley   +1 more source

Drivers of Microbiome Composition Among Helminth Parasites Sharing the Same Insectivorous Bat Host

Molecular Ecology, Volume 35, Issue 10, May 2026.
ABSTRACT Parasitic metazoans are increasingly recognised to form close associations with microbial taxa. Under the holobiont concept, these associations are an eco‐evolutionary unit under joint selection. However, for most parasitic helminth species and particularly those associated with wildlife, these interactions and their effect on parasite ...
Nallely G. Ruiz‐Torres, Shamayim Martínez‐Sánchez, Arit de León‐Lorenzana, Ricardo A. Mercado‐Juárez, Priscila M. Salloum, Robert Poulin, Osiris Gaona, Luisa I. Falcón, Oscar Rico‐Chávez   +8 more
wiley   +1 more source

A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu, Alex Liang, Benjamin U. Hoffman, Dawn M. Schiehser, Oliver Case, Alan Simmons, Ruth Klaming, Andres Gottfried‐Blackmore, Ravinder K. Mittal, Christopher Puleo, Hubert Lim, Imanuel Lerman   +11 more
wiley   +1 more source

How Different Traditional and Modern Coffee Brewing Methods Affect Its Aroma, Chemistry, Health Effects and Safety Attributes?—A Comprehensive Review to Maximize Coffee Brew Quality

eFood, Volume 7, Issue 2, April 2026.
This review article provides a comprehensive analysis of coffee pre‐brewing techniques, focusing on the methodology and key parameters involved in each coffee brewing process. It also summarizes how different brewing methods affect the coffee metabolome, antioxidant levels, aroma, and physicochemical features.
Enas A. El‐Hawary, Hania A. Guirguis, Nik Muhammad Azhar Nik Daud, Mohd Asraf Zainudin, Ahmed Mediani, Mohamed A. Farag   +5 more
wiley   +1 more source

Boat electrofishing survey of the upper Turitea Reservoir, Palmerston North. [PDF]

, 2009
The upper Turitea Reservoir is a 12-ha reservoir that supplies water to the city of Palmerston North (Figure 1). It was constructed in 1957 and is located in the foothills of the Tararua Ranges at 40.43208°S, 175,67669°E. The 2,300 hectare catchment area
Powrie, Warrick, Hicks, Brendan J., Brijs, Jeroen, Ling, Nicholas, Bell, Dudley G., Blair, Jennifer Marie   +5 more
core  

Microbiological Characterization of Baru Nuts From the Cerrado Biome, Brazil

Journal of Food Science, Volume 91, Issue 4, April 2026.
ABSTRACT This study aimed to microbiologically characterize baru nuts, a seed widely consumed in Brazil with growing relevance in the export market. Analyses were conducted for mesophilic and thermophilic aerobic spore‐forming bacteria, total mesophilic aerobes, Enterobacteriaceae, Salmonella, Staphylococcus aureus, lactic acid bacteria, molds, and ...
Clara Mariana Gonçalves Lima, Dionísio Pedro Amorim‐Neto, Bruna Godoi de Castro, Ana Luísa Perini Leme Giordano, Beatriz Machado Dal Pian, Matheus Péricles Silva Láscaris, Luana Cristina da Silva Ramos, Angélica Zaninelli Schreiber, Luisa Freire Colombo, Anderson S. Sant'Ana   +9 more
wiley   +1 more source

Diagnosis and Treatment of Multiseptate Gallbladder with Recurrent Abdominal Pain [PDF]

, 2011
Laparoscopic cholecystectomy is usually performed for gallstones or polyp of the gallbladder. Multiseptate gallbladder is a rare congenital malformation.
Özen, Saadet, Ender Evcik, Omer Yoldas, Bilgin, Bülent Cağlar, Saadet Ozen, Selma Bilgin, Karaca, Turgut, Turgut Karaca, Bilgin, Selma, Bulent Caglar Bilgin, Yoldaş, Ömer, Evcik, Ender   +11 more
core   +1 more source

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source