PET/PDT theranostics: Synthesis and biological evaluation of a peptide-targeted gallium porphyrin [PDF]
, 2015 The development of novel theranostic agents is an important step in the pathway towards personalised medicine, with the combination of diagnostic and therapeutic modalities into a single treatment agent naturally lending itself to the optimisation and ...
Boyle, Ross W. +3 more
core +1 more source
Radiolabeling Strategies for Tumor-Targeting Proteinaceous Drugs
Molecules, 2014 Owing to their large size proteinaceous drugs offer higher operative information content compared to the small molecules that correspond to the traditional understanding of druglikeness.
Grant Sugiura +4 more
doaj +1 more source
Sarcoidosis-associated hepatocellular carcinoma [PDF]
, 2010 Sarcoidosis is a systemic granulomatous inflammation of unknown etiology, and seems to involve the liver parenchyma in most cases. However, sarcoidosis-associated hepatocellular carcinoma is rare. We report here a case in which a hepatocellular carcinoma
Aiko, Satoshi +7 more
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World Journal of Nuclear Medicine, 2015 Dose calibrator linearity testing is indispensable for evaluating the capacity of this equipment in measuring radioisotope activities at different magnitudes, a fundamental aspect of the daily routine of a nuclear medicine department, and with an impact ...
José Willegaignon +7 more
doaj +1 more source
NEMA NU 2-2007 performance characteristics of GE Signa integrated PET/MR for different PET isotopes [PDF]
, 2019 BackgroundFully integrated PET/MR systems are being used frequently in clinical research and routine. National Electrical Manufacturers Association (NEMA) characterization of these systems is generally done with F-18 which is clinically the most relevant
D'Asseler, Yves +5 more
core +1 more source
Folate-Based Radiotracers for PET Imaging—Update and Perspectives
Molecules, 2013 The folate receptor (FR) is expressed in many tumor types, among those ovarian and lung cancer. Due to the high FR affinity of folic acid, it has been used for targeting of FR-positive tumors, allowing specific delivery of attached probes to the ...
Cristina Müller
doaj +1 more source
Ga(III) chelates of amphiphilic DOTA-based ligands : synthetic route and in vitro and in vivo studies [PDF]
, 2011 In this work we report a synthetic strategy of amphiphilic DOTA-based chelators bearing a variable size α-alkyl chain at one of the pendant acetate arms (from six to fourteen carbon atoms), compatible with their covalent coupling to amine-bearing ...
André, João P. +3 more
core +1 more source
Feasibility of isotope harvesting at a projectile fragmentation facility: ⁶⁷Cu [PDF]
, 2014 The work presented here describes a proof-of-principle experiment for the chemical extraction of (67)Cu from an aqueous beam stop at the National Superconducting Cyclotron Laboratory (NSCL).
Essenmacher, Scott +8 more
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NMR spectroscopy of Group 13 metal ions : biologically relevant aspects [PDF]
, 2003 ReviewIn spite of the fact that Group 13 metal ions (Al(III), Ga(III), In(III) and Tl(I)/(III)) show no main biological role, they are NMR-active nuclides which can be used in magnetic resonance spectroscopy of biologically relevant systems.
André, João P., Mäcke, Helmut
core +1 more source
Comparative evaluation of [(99m)tc]tilmanocept for sentinel lymph node mapping in breast cancer patients: results of two phase 3 trials. [PDF]
, 2013 BackgroundSentinel lymph node (SLN) surgery is used worldwide for staging breast cancer patients and helps limit axillary lymph node dissection.
Avisar, Eli +15 more
core +2 more sources