Results 131 to 140 of about 175,078 (308)
Boreas, EarlyView.Land snail successions in the lower Rhône valley allow us to reconstruct the postglacial recolonization. From the Lateglacial period onwards, Mediterranean steppe communities appeared. The arrival of forest taxa was significantly delayed by aridity. The question of glacial refugia, both local and distant, primarily concerned Mediterranean species of ...
Frédéric Magnin
wiley +1 more source
Cardiotoxicity of BRAF/MEK inhibitors
British Journal of Pharmacology, EarlyView.Abstract Rapidly accelerated fibrosarcoma type B/B‐Raf proto‐oncogene, serine/threonine kinase (BRAF) and mitogen‐activated protein kinase (MEK) inhibitors have transformed outcomes in cancer therapy, particularly in melanoma. However, cardiovascular toxicities are increasingly recognized in real‐world clinical practice.
Katharina Seuthe +4 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Background and Purpose Neuronal plasticity enables the brain to adapt to internal and external demands by dynamically regulating synaptic connectivity and emotional circuitry. Impaired neuroplasticity represents a core pathophysiological framework of major depressive disorder, one of the leading causes of disability worldwide. Chronic stress is a major
Paola Brivio +11 more
wiley +1 more source
, 2008 Discriminant Partial Least Squares for Compositional data (DPLS-CO) was recently proposed by Gallo (2008). The aim of this paper is to show that DPLS-CO is a better dimensionality reduction technique than the LogContrats Principal Component Analysis ...
GALLO, Michele, MAHDI S.
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The role of structural transformation in regional convergence in Japan: 1874–2008
The Economic History Review, EarlyView.Abstract Japan's regional convergence of productivity levels throughout the twentieth century can be best described as a cumulative process of ‘catching up, forging ahead, and falling behind’. Using a novel dataset spanning 135 years (1874–2008), this study finds support for a crucial role played by structural transformation in convergence. The pace of
Kyoji Fukao, Saumik Paul
wiley +1 more source
Senza attraversare le frontiere. Le migrazioni interne dall'Unità a oggi
, 2012 La prima narrazione complessiva delle migrazioni interne al nostro paese, dall'Unità all'inizio del Terzo Millennio. Stefano Gallo racconta i mutamenti economici tra aree forti e aree deboli (città/campagna, Nord/Sud); indaga i soggetti e le norme che ...
Stefano Gallo
core
Scientia Agropecuaria, 2015 La cinética de degradación de la betacianinas, betaxantinas y vitamina C a 30 °C, 40 °C y 50 ºC fue evaluada en una bebida a base de betarraga y miel de abeja, utilizando los modelos cinéticos de orden cero, primer y segundo orden; así como el modelo de ...
William Sánchez-Chávez +3 more
doaj
The FEBS Journal, EarlyView.A tandem fluorescent mCherry–EGFP–LC3 reporter enables live‐cell visualisation of autophagy–lysosome dynamics in naked mole‐rat skin fibroblasts. Chloroquine‐induced lysosomal stress promotes accumulation of neutral LC3‐positive compartments and triggers pronounced LC3‐associated vacuolation.
Fangze Tong +6 more
wiley +1 more source