Results 111 to 120 of about 102,035 (308)

NG peptides: A novel family of neurophysin-associated neuropeptides [PDF]

, 2010
NOTICE: this is the author’s version of a work that was accepted for publication in GENE. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be ...
Bromham, De Bree, De Bree, Elphick, Gwee, Inoue, Ivell, Iwakoshi, Kato, Kawada, Legros, Maurice R. Elphick, Putnam, Reinscheid, Roth, Stafflinger, Terhzaz, Ukena, Van Kesteren, Verleyen, Xu   +20 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Potencial probiótico de cepas nativas para uso como aditivos en la alimentación avícola

Revista Colombiana de Biotecnología, 2012
Título en ingles: Probiotic potential of native strains, for as feed additives for poultry Resumen: Se evaluó in vitro el potencial probiótico de cepas nativas aisladas de las heces de pollos asilvestrados (Gallus gallus) pertenecientes a los géneros ...
Cecilia Lara Mantilla, Ángela Burgos Portacio   +1 more
doaj  

Narrowing the wingless-2 mutation to a 227 kb candidate region on chicken chromosome 12. [PDF]

, 2018
Wingless-2 (wg-2) is an autosomal recessive mutation in chicken that results in an embryonic lethal condition. Affected individuals exhibit a multisystem syndrome characterized by absent wings, truncated legs, and craniofacial, kidney, and feather ...
Cheng, HH, Delany, ME, Gitter, CL, Kaya, M, May, B, O'Hare, EA, Webb, AE, Youngworth, IA   +7 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

A Gallus gallus Model for Determining Infectivity of Zoonotic Campylobacter

Frontiers in Microbiology, 2019
To better understand public health implications of waterfowl as reservoirs for zoonotic sources of Campylobacter in recreational waters, we developed a Gallus gallus (chick) model of infection to assess the pathogenicity of environmental isolates of ...
Dennis Lye, Ian Struewing, Theresa M. Gruber, Kevin Oshima, Eric N. Villegas, Jingrang Lu   +5 more
doaj   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Chromosome-level Genome Assembly of Korean Long-tailed Chicken and Pangenome of 40 Gallus gallus Assemblies

Scientific Data
This study presents the first chromosome-level genome assembly of the Korean long-tailed chicken (KLC), a unique breed of Gallus gallus known as Ginkkoridak.
Hanshin D. Shin, Wonchoul Park, Han-ha Chai, Youngho Lee, Jaehoon Jung, Byung June Ko, Heebal Kim   +6 more
doaj   +1 more source

Complete Nucleotide Sequence of Mitochondrial Genome in Silkie Fowl (Gallus gallus var. domesticus)

The Journal of Poultry Science, 2004
Whole mitochondrial DNA of the Silkie fowl (Gallus gallus var. domesticus) was sequenced in order to elucidate the genetic position of the Silkie fowl in its related species based on mitochondrial DNA sequence. The length of Silkie mitochondrial DNA was
Yasuhiko Wada, Yoshiyuki Yamada, Masahide Nishibori, Hiroshi Yasue   +3 more
doaj   +1 more source