Results 61 to 70 of about 102,035 (308)

Evaluation of three family farms producing organic eggs in southern Brazil: animal welfare and biosecurity. [PDF]

open access: yes, 2011
Three family farms producing organic eggs with 5,000, 250 and 100 birds, of the species Gallus gallus domesticus, have been studied. The farms are located in southern Brazil.
Bossardi, Melissa, Escosteguy, Angela
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Dynamic transcriptome and chromatin architecture in granulosa cells during chicken folliculogenesis

open access: yesNature Communications, 2022
The domestic chicken Gallus gallus domesticus is a classic model for the study of folliculogenesis. Here the authors integrate multi-omics analyses characterizing the dynamic transcriptome and chromatin architecture in granulosa cells during chicken ...
Diyan Li   +17 more
doaj   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Melatonin receptor expression in the zebra finch brain and peripheral tissues [PDF]

open access: yes, 2012
The circadian endocrine hormone melatonin plays a significant role in many physiological processes such as modulating sleep/wake cycle and oxidative stress.
Brandstaetter, Roland   +2 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

KULUÇKA SONRASI DÖNEMDE TAVUK (GALLUS GALLUS DOMESTICA) DUODENUM GOBLET HÜCRELERİNİN HİSTOKİMYASAL YAPISI

open access: yesSüleyman Demirel Üniversitesi Fen-Edebiyat Fakültesi Fen Dergisi, 2009
Özet: Kuluçkadan sonra 7 ve 60 günlük tavukların (Gallus gallus domestica) duodenumunda yer alan Goblet hücrelerindeki glikoprotein içeriği klasik histokimyasal yöntemlerle belirlendi.
Dilek DİLER   +2 more
doaj  

Caesar Constantius Gallus (351–354 AD) and His Military Policy at the Near East Provinces of the Late Roman Empire

open access: yesАнтичная древность и средние века, 2020
The paper addresses the military-administrative activities of Constantius Gallus, a nephew of Emperor Constantius II (337–361), who administered the Late Roman Empire’s eastern provinces from 351 to 354 on behalf of Constantius II, holding the title of ...
Evgenii Aleksandrovich Mekhamadiev
doaj   +1 more source

Genetic diversity of Gallus sp. in Southeast Asia based on d-lopp: In silico study

open access: yesJournal of Advanced Veterinary and Animal Research, 2023
Objective: This study was conducted to analyze the matrilineal structure of Gallus sp. in Southeast Asia, especially in the D-loop region. Materials and Method: A total of 563 sequences from eight countries (Laos, Myanmar, Vietnam, Malaysia, Indonesia ...
Zultinur Muttaqin   +2 more
doaj   +1 more source

Identification and characterisation of 17 polymorphic candidate genes for response to parasitic nematode (Trichostrongylus tenuis) infection in red grouse (Lagopus lagopus scotica) [PDF]

open access: yes, 2016
Acknowledgements This study was funded by a BBSRC studentship (MA Wenzel) and NERC Grants NE/H00775X/1 and NE/D000602/1 (SB Piertney). We are grateful to Jacob Hoglund for providing willow grouse samples, Mario Roder, Keliya Bai, Marianne James, Matt ...
Paterson, Steve   +3 more
core   +1 more source

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