Results 171 to 180 of about 4,684 (195)

Triptolide attenuate the oxidative stress induced by LPS/D‐GalN in mice

Journal of Cellular Biochemistry, 2012
AbstractTriptolide, a diterpene triepoxide, is one of the major components of most functional extracts of Tripterygium wilfordii Hook f, which is known to have various biological effects, including immunosuppressive, anti‐inflammatory and anti‐tumor functions. We studied the inhibitory effect of triptolide on endotoxemia (ETM)‐induced oxidative stress,
Yan, Lu, Xiaofeng, Bao, Tingzhe, Sun, Jiafa, Xu, Wei, Zheng, Pingping, Shen   +5 more
openaire   +2 more sources

Antioksidacijski profil galne kiseline

2010
Antioksidansi u biološkim sustavima sprječavaju generiranje reaktivnih oblika kisika (ROS- Reactive Oxygen Species), poput superoksidnog, hidroksidnog i peroksidnog radikala, te singletnog kisika, koji u biološkim sustavima nastaju kao sporedni produkti bioloških reakcija i/ili pod utjecajem različitih egzogenih faktora.
Carev, Ivana, Skroza, Danijela, Generalić, Ivana, Burčul, Franko, Muštra, Jelena   +4 more
openaire   +2 more sources

Porcine N -Acetylgalactosamine 6-Sulfatase (GALNS) cDNA Sequence and Expression in Developing Teeth

Connective Tissue Research, 2002
Mucopolysaccharidosis type IVA (Morquio A syndrome, MPS IVA) is a rare, autosomal recessive disorder with a prevalence of 1 in 170,000 live births. It is caused by a deficiency of N-acetylgalactosamine 6-sulfatase (GALNS), a lysosomal hydrolase encoded by a gene on human chromosome 16q24.3.
Yasuo Yamakoshi, , Chuhua Zhang
exaly   +3 more sources

Interleukin-23 mediates the pathogenesis of LPS/GalN-induced liver injury in mice

International Immunopharmacology, 2017
Interleukin-23 (IL-23) is required for T helper 17 (Th17) cell responses and IL-17 production in hepatitis B virus infection. A previous study showed that the IL-23/IL-17 axis aggravates immune injury in patients with chronic hepatitis B virus infection.
Suxia Bao, Qiang Zhao, Jianming Zheng, Ning Li, Chong Huang, Mingquan Chen, Qi Cheng, Mengqi Zhu, Kangkang Yu, Chenghai Liu, Guangfeng Shi   +10 more
openaire   +2 more sources

Elektrokemijska karakterizacija galne kiseline

2021
U ovom diplomskom radu ispitivana su elektrokemijska svojstva galne kiseline u različitim puferima i realnim uzorcima uporabom diferencijalne pulsne voltametrije. Vrijednosti pH pufera su varirale od pH = 3, 0 do pH = 9, 5. Cilj rada bio je ispitati utjecaj pH na potencijal oksidacijskog strujnog vrha galne kiseline, istražiti utjecaj koncentracije ...
openaire   +1 more source

Stress-induced exacerbation of LPS/GalN liver injury

2018
Stress is a key regulator of homeostasis in the body. However, aberrant activation of the stress response has been implicated in predisposing to, and exacerbating processes that underlie a variety of pathological conditions including mood disorders (anxiety/depression), cardiovascular disease, gastrointestinal disease and liver disease.
openaire   +2 more sources

Polymorphism in the GALNS gene

Human Molecular Genetics, 1994
S, Tomatsu, S, Fukuda, H, Iwata, T, Ogawa, K, Sukegawa, T, Orii   +5 more
openaire   +2 more sources

galnes, n.

2023
openaire   +1 more source

Pharmacological chaperones as an alternative to increase GALNS activity in mucopolysaccharidosis type IVA

Molecular Genetics and Metabolism, 2023
Luisa Prada, Diego A. Suárez, Carlos Javier Alméciga-Díaz   +2 more
openaire   +1 more source

Computational approach for the design of a less immunogenic GALNS enzyme

Molecular Genetics and Metabolism, 2014
Sergio Olarte, Alexander Rodríguez-López, Carlos J. Almeciga-Diaz   +2 more
openaire   +1 more source