Results 91 to 100 of about 58,552 (294)

Reliable AI Platform for Monitoring BCI Caused Brain Injury and Providing Real‐Time Protection

open access: yesAdvanced Science, EarlyView.
BrainGuard enables real‐time and interpretable assessment of brain injury caused by brain computer interface (BCI). Using feature‐based Gaussian process (GP) emulators trained on limited biomechanical data, it efficiently predicts full‐field strain and constructs patient‐specific digital brain twins to support clinical diagnosis and long‐term BCI ...
Chufan He   +3 more
wiley   +1 more source

Unveiling Global Diversity of Patescibacteriota and Functional Interactions with Host Microbes

open access: yesAdvanced Science, EarlyView.
Patescibacteriota represents a diverse group of ultra‐small epibiotic bacteria, which is largely overlooked. By integrating ribosomal protein S3‐based community profiling with MAG‐based metabolic potential analyses, this study provides new insights into their distribution, diversity, and potential interactions with other bacteria across diverse ...
Yanhan Ji   +12 more
wiley   +1 more source

Advanced Stem Cell Therapy: 3D‐Bioprinted Brain‐Like Transplants for Alzheimer's Disease‐Like Dementia

open access: yesAdvanced Science, EarlyView.
A tri‐component biomimetic bioink(gelatin/alginate/fibrinogen) is developed to protect cells in critical pathological environments in AD. Using this bioink, a 3D‐printed NPC construct optimized for hippocampal transplantation is provided to improve cell retention and differentiation in an AD‐like model. This approach enhances memory recovery and offers
Ke Gai   +12 more
wiley   +1 more source

A Hydrodynamic Bioreactor for High‐Yield Production of Extracellular Vesicles from Stem Cell Spheroids with Defined Cargo Profiling

open access: yesAdvanced Science, EarlyView.
This study harnesses hydrodynamic flows to generate, confine and stimulate stem cell spheroids, enabling the large‐scale production of extracellular vesicles (EVs). This innovative method not only streamlines spheroid formation and subsequent EV release in a single, integrated process, but also ensures the generation of EVs with enhanced biological ...
Solène Lenoir   +7 more
wiley   +1 more source

Modulating Purothionin Accumulation and Signal Peptide Cleavage Fine‐Tunes Wheat Flour Gluten Properties to Improve Cookie‐Making Quality

open access: yesAdvanced Science, EarlyView.
Dual genetic strategies for improving wheat processing quality by regulating purothionin accumulation to modulate gluten quantity and quality. The first strategy involves targeting signal peptide (SP) cleavage sites (e.g., through mutation) to indirectly reduce gluten content, thereby disrupting gluten network formation.
Yijie Liu   +16 more
wiley   +1 more source

CircTspan3 Promotes Cartilage Development Through ANNEXIN A2‐Mediated Ferroptosis and Apoptosis Inhibition and Exosome‐Mediated Paracrine Signaling

open access: yesAdvanced Science, EarlyView.
This study reveals that XBP1s drives production of circTspan3, a circular RNA that strengthens cartilage by boosting anabolic activity and limiting cell death. Phosphorylated ANXA2 directs circTspan3 into exosomes, enabling paracrine repair. Exosomal circTspan3 expands growth‐plate cartilage and promotes in vivo regeneration, highlighting its promise ...
Yiming Pan   +16 more
wiley   +1 more source

Broadband All‐Optical Memtransistor Based on Organic Cocrystals for Noise‐Robust Motion Recognition

open access: yesAdvanced Science, EarlyView.
This work presents an all‐optical synaptic transistor using DTT‐TCNQ organic charge transfer cocrystals, achieving broadband bidirectional modulation (395–808 nm) with highly linear synaptic plasticity (nonlinearity coefficients αp = 0.00191, αd = 0.00305).
Zhaohui Cai   +8 more
wiley   +1 more source

Gambling addiction [PDF]

open access: yesBMJ, 2011
Henrietta, Bowden-Jones, Sanju, George
openaire   +2 more sources

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