Results 91 to 100 of about 77,923 (277)

Game changer: understanding and managing hypertrophic cardiomyopathy in athletes [PDF]

open access: yesEuropean Journal of Translational and Clinical Medicine
Physiological left ventricular hypertrophy in athletes often blurs the diagnostic line with hypertrophic cardiomyopathy (HCM), necessitating a critical differentiation to avert sudden cardiac death (SCD).
Maria Kulak   +7 more
doaj   +1 more source

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

open access: yesAdvanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley   +12 more
wiley   +1 more source

Additive Manufacturing: A Game Changer in Supply Chain Design

open access: yesLogistics, 2019
Additive Manufacturing (AM) is a digital manufacturing technology that enables companies to rethink their supply chain (SC) design. By means of literature synthesis, we build new knowledge about the mechanisms AM induces to improve SC design and ...
Victor Verboeket, Harold Krikke
doaj   +1 more source

The Force Awakens: the Individualistic and Contemporary Heroine [PDF]

open access: yes, 2017
Star Wars Episode VII: The Force Awakens is not the hero’s journey as George Lucas previously conceptualized it. Instead, the story line of The Force Awakens leads me to believe that it creates a new iteration of the hero myth.
Doctor, Payal
core   +1 more source

Could Turkey’s new parties change the political balance? EPC Policy Brief 13 March 2020 [PDF]

open access: yes, 2020
New political trends are unfolding in Turkey. Recently established political parties have raised hopes for change in the country, impacting the political balance between the government and the opposition.
Paul, Amanda, Seyrek, Demir Murat
core  

Unleashing the Power of Machine Learning in Nanomedicine Formulation Development

open access: yesAdvanced Functional Materials, EarlyView.
A random forest machine learning model is able to make predictions on nanoparticle attributes of different nanomedicines (i.e. lipid nanoparticles, liposomes, or PLGA nanoparticles) based on microfluidic formulation parameters. Machine learning models are based on a database of nanoparticle formulations, and models are able to generate unique solutions
Thomas L. Moore   +7 more
wiley   +1 more source

Region‐to‐Region Unidirectional Connection In Vitro Brain Model for Studying Directional Propagation of Neuropathologies

open access: yesAdvanced Functional Materials, EarlyView.
A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang   +9 more
wiley   +1 more source

A cultura humana e necessidades ecossistémicas como fundamentação da inovação no design de casas de banho [PDF]

open access: yes, 2019
: Proposed paper is a part of the ongoing PhD research in design with focus on the research of existing environmental and social requirements for the sustainable innovation within urban sanita_on, focused on toilet design.
Ferreira, Ana Margarida   +2 more
core  

An All‐Optical Driven Bio‐Photovoltaic Interface for Active Control of Live Cells

open access: yesAdvanced Functional Materials, EarlyView.
Bio‐photovoltaic Interface (BIO‐PV‐I) for live cell manipulation is presented. BIO‐PV‐I can be activated non‐invasively and remotely to control the spatial motility, adhesion, and morphology of cells adhering to it. BIO‐PV‐I uses a patterned light‐induced electric potential in iron‐doped lithium niobate crystals whose light‐driven and reversible nature,
Lisa Miccio   +8 more
wiley   +1 more source

China's ETS: A vote of confidence in carbon markets ahead of Paris. CEPS Commentary, 12 October 2015 [PDF]

open access: yes, 2015
In this CEPS commentary, Andrei Marcu welcomes the recent announcement by President Xi Jinping that China will start a national emissions trading scheme in 2017.
Marcu, Andrei
core  

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