Results 31 to 40 of about 77,923 (277)

mHealth Research Applied to Regulated and Unregulated Behavioral Health Sciences [PDF]

open access: yes, 2020
Behavioral scientists are developing new methods and frameworks that leverage mobile health technologies to optimize individual level behavior change. Pervasive sensors and mobile apps allow researchers to passively observe human behaviors “in the wild ...
Nebeker, Camille
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Setting the record straight on the Malayan counterinsurgency strategy: interview with Karl Hack [PDF]

open access: yes, 2011
You are a long time researcher and observer of the Malayan Emergency. What were the core key ingredients that broke the back of the communist insurgents in the Malayan Emergency? The primary cause for putting the campaign on a firmly winning path?
Hack, Karl
core  

Fisheye Photogrammetry to Survey Narrow Spaces in Architecture and a Hypogea Environment [PDF]

open access: yes, 2018
Nowadays, the increasing computation power of commercial grade processors has actively led to a vast spreading of image-based reconstruction software as well as its application in different disciplines.
Baiocchi, Valerio   +9 more
core   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Hybrid cargo airships: a humanitarian logistic game changer? [PDF]

open access: yesJournal of Humanitarian Logistics and Supply Chain Management, 2017
Purpose – Recent advances in aviation technology have seen the development of helium-filled “hybrid cargo airships” (HCAs) which have the potential to convey large payloads over significant distances at relatively low cost and with a small carbon ...
Peter Tatham, Craig Neal, Yong Wu
doaj   +1 more source

Game of zones. The quest for influence in Europe’s neighbourhood. Egmont Paper No. 67, June 2014 [PDF]

open access: yes, 2014
Introduction. Russia’s annexation of the Crimea and subsequent meddling in Ukraine does not constitute a game-changer. It is just a reminder that at least since the war with Georgia in 2008 Russia has been and still is playing the same game: a “game of ...
Biscop, Sven
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

E-Management as a Game Changer in Local Public Administration

open access: yesEconomies, 2022
The rapid development of digital technologies provides an efficient way to overcome the drawbacks of traditional management. E-management, a new form of management, is attracting much attention worldwide.
Neringa Vilkaite-Vaitone   +1 more
doaj   +1 more source

Game Changer: Investing in Digital Play to Advance Children's Learning and Health [PDF]

open access: yes, 2009
Based on a literature review and interviews with digital learning experts, explores how digital games can foster skills and knowledge for better academic performance and health.
Ann My Thai   +3 more
core  

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