Results 61 to 70 of about 6,511,477 (348)
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon+13 more
wiley +1 more source
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez+5 more
wiley +1 more source
The Game Semantics of Game Theory
We use a reformulation of compositional game theory to reunite game theory with game semantics, by viewing an open game as the System and its choice of contexts as the Environment. Specifically, the system is jointly controlled by $n \geq 0$ noncooperative players, each independently optimising a real-valued payoff.
openaire +2 more sources
ABSTRACT Nontraditional students represent a substantial number and significant percentage of students in higher education. While these adult learners have similarities, they also span 50+ years with generational differences. At the same time, online learning is on the rise, offering opportunities and challenges for nontraditional students and those ...
Brittany Hyden, Catherine A. Cherrstrom
wiley +1 more source
In recent years, several global events have severely disrupted economies and social structures, undermining confidence in the resilience of modern societies.
Florian Schunck+3 more
doaj +1 more source
Game Theory and Emotions [PDF]
To illustrate the rational-choice modeling of emotions, a game-theoretic model of frustration, in which players respond in anger to their lack of control, is developed. Of the 57 distinct 2 × 2 strict ordinal conflict games, 12 turn out to be `frustration games', in four of which `threat power', based on the theory of moves, offers relief to the ...
openaire +3 more sources
A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems
A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam+2 more
wiley +1 more source
研究元件具有无失效试验数据的贮备系统可靠性的评定问题.由无失效试验数据下元件可靠性置信下限的定义,得到元件分布参数的fiducial分布.并以此为出发点,对基于指数寿命型元件的无失效成败型试验数据、贮备系统的切换开关的成败型试验数据,在开关的成功概率分别为已知和未知的情形下,导出了由指数寿命型元件组成的贮备系统可靠性的fiducial置信下限的计算公式,并给出了算例.
JIANGRen-bin(蒋仁斌)+1 more
doaj +1 more source
Game Theory and Game Mechanics Design [PDF]
This paper focuses on the significance of game balance in games and explores the application of game theory concepts for designing and analyzing balanced gameplay.
Pi Jiasheng
doaj +1 more source
Chromatin, which organizes DNA, changes its structure to adapt to stress like high oxygen levels (hyperoxia), which can damage cells. Researchers developed a technique to observe these changes and found variability in how different parts of chromatin remodel.
Lauren Monroe+4 more
wiley +1 more source