Results 61 to 70 of about 6,194,156 (311)
Zhejiang Daxue xuebao. Lixue ban, 2010 研究元件具有无失效试验数据的贮备系统可靠性的评定问题.由无失效试验数据下元件可靠性置信下限的定义,得到元件分布参数的fiducial分布.并以此为出发点,对基于指数寿命型元件的无失效成败型试验数据、贮备系统的切换开关的成败型试验数据,在开关的成功概率分别为已知和未知的情形下,导出了由指数寿命型元件组成的贮备系统可靠性的fiducial置信下限的计算公式,并给出了算例.
JIANGRen-bin(蒋仁斌) +1 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Three essays on game theory [PDF]
, 2007 The main text of this thesis is divided into three chapters. The three papers are contributions to the literature on equilibrium refinements in noncooperative game theory. Each chapter can be read independently of the rest.
González Pimienta, Carlos
core +1 more source
Application of Game Theory in Integrated Energy System Systems: A Review
IEEE Access, 2020 With the rapid development of society, global energy is in short supply. China has put forward an integrated energy system focusing on interconnecting energy resources and harnessing their complementary advantages to address the energy crisis, thus no ...
Jun He +6 more
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
, 2023 Evolutionary game theory originated in population biology from the realisation that frequency-dependent fitness introduced a strategic element into evolution. Since its development, evolutionary game theory has been adopted by many social scientists, and
Alexander, J McKenzie
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Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Game Theory: The Next Stage [PDF]
, 1999 This paper surveys some recent developments in (non-cooperative) game theory and provides an outlook on the near future of that theory. In particular, attention is focused on the limitations inherent in normative game theory and on attempts to construct a behavioral version of the theory that incorporates aspects of procedural and bounded rationality ...
openaire +4 more sources