Results 81 to 90 of about 2,624,050 (373)
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
The use of multiplayer game theory in the modeling of biological populations [PDF]
, 2003 The use of game theory in modeling the natural world is widespread. However, this modeling mainly involves two player games only, or "playing the field" games where an individual plays against an entire (infinite) population.
Broom, M.
core +1 more source
Reachability Games and Parity Games
, 2022 Parity games are positionally determined. This is a fundamental and classical result. In 2010, Calude et al. showed a breakthrough result for finite parity games: the winning regions and their positional winning strategies can be computed in quasi-polynomial time. In the present paper we give a self-contained and detailed proofs for both results.
Volker Diekert, Manfred Kufleitner
openaire +2 more sources
Simple Games Versus Weighted Voting Games [PDF]
SSRN Electronic Journal, 2018 A simple game $(N,v)$ is given by a set $N$ of $n$ players and a partition of $2^N$ into a set $\mathcal{L}$ of losing coalitions $L$ with value $v(L)=0$ that is closed under taking subsets and a set $\mathcal{W}$ of winning coalitions $W$ with $v(W)=1$. Simple games with $ = \min_{p\geq 0}\max_{W\in {\cal W},L\in {\cal L}} \frac{p(L)}{p(W)}<1$ are
Hof, F. +3 more
openaire +5 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
European PsychiatryIntroduction In Cue-Exposure-Therapy (CET), clients are exposed to triggers through objects, people and environments that arouse craving (Sinha et al. Neuropsychopharmacol. 2009;34 1198–1208).
V. J. J. A. Buwalda +3 more
doaj +1 more source
, 2016 We introduce Celebrity games, a new model of network creation games. In this model players have weights (W being the sum of all the player's weights) and there is a critical distance ß as well as a link cost a.
Blesa Aguilera, Maria Josep +4 more
core +2 more sources
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Strong Nash Equilibria in Games with the Lexicographical Improvement Property [PDF]
, 2009 We introduce a class of finite strategic games with the property that every deviation of a coalition of players that is profitable to each of its members strictly decreases the lexicographical order of a certain function defined on the set of strategy ...
Harks, Tobias +2 more
core +3 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source