Results 251 to 260 of about 20,463 (308)

PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility

Advanced Science, EarlyView.
PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao, Qianting Zhang, Wei Xu, Anxuan Fang, Haomang Xu, Cheng Qiu, Lugeng He, Chao Yu   +7 more
wiley   +1 more source

Assessing the Impact of External and Internal Factors on Emergency Department Overcrowding. [PDF]

Healthcare (Basel)
Ahmed A, Aram KY, Alzeen M, Vural O, Booth J, Lindsey BF, Ozaydin B.   +6 more
europepmc   +1 more source

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

Advanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen, Xiao Guan, Kexu Xiong, Xiaoyi Shi, Luyao Wu, Chuanxin Su, Jun Zhao, Rongzhen Liang, Huimin Wang, Junlong Dang, Ye Chen, Yiding Xiong, Chi Zhou, Futao Zhao, Zhenhang Zhu, Xiaoli Fan, Li Zhou, Nancy Olsen, Yutong Jiang, Song Guo Zheng   +19 more
wiley   +1 more source

NeuroPlayNet: a multimodal AI framework for real-time cognitive-aware strategy optimization in professional basketball. [PDF]

Sci Rep
Liang Y, Guo X, Zhang J, Du X.
europepmc   +1 more source

Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro

Advanced Science, EarlyView.
The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel, Anna‐Sophie Schlemmer, Andrea W. Eiken, Zachary W. Wagoner, Dennis Vöhringer, Lena Christ, Alex Dulovic, Patrick Marsall, Madeleine Fandrich, Eduardo J. S. Brás, Julia Marzi, Friederike Bärhold, Julia Philipp, Sven Becker, Lisa E. Wagar, Peter Loskill   +15 more
wiley   +1 more source

Effectiveness of gamified swallowing exercise in adults with dysphagia: protocol for a systematic review and meta-analysis. [PDF]

Syst Rev
Liu J, Xu X, Ou M.
europepmc   +1 more source

Paralympic health: emerging trends and innovations. [PDF]

Front Sports Act Living
Winckler C, Neto FR, Gomes Costa RR, Loturco I, Lima Trigo E, Miranda AJ, Santos LG.   +6 more
europepmc   +1 more source

Gambling-like gaming, offline leisure, and help-seeking in problematic gaming among Flemish adolescents: a three-wave longitudinal study. [PDF]

Front Psychol
Geudens M, Bradt L, De Cock R, Zaman B, Grosemans E.   +4 more
europepmc   +1 more source

Enhancing Extended Reality Technology for Neuromusculoskeletal Rehabilitation: Recommendations for the Development of Clinically Relevant Serious Games. [PDF]

J Pers Med
Moevus A, Vu AK, Menezes KRS, Levin MF, Kairy D.   +4 more
europepmc   +1 more source

Winning beyond scoring: an explainable machine learning framework for identifying key performance indicators in the Chinese Basketball Association. [PDF]

BMC Sports Sci Med Rehabil
Dong R, Peng Y, Liu Q, Gómez-Ruano MA, Zhang S, Xu X, Yang B, Liu H.   +7 more
europepmc   +1 more source