Results 81 to 90 of about 68,672 (267)

The 1st INTEGRAL SPI-ACS Gamma-Ray Burst Catalogue

, 2005
We present the sample of gamma-ray bursts detected with the anti-coincidence shield ACS of the spectrometer SPI on-board INTEGRAL for the first 26.5 months of mission operation (up to Jan 2005).
A. Rau, A. v. Kienlin, , Arend, Band, Beckmann, Cline, Dezalay, Duncan, Fishman, Fishman, G. G. Lichti, Hakkila, Horvath, Hurley, Hurley, K. Hurley, Klebesadel, Kouveliotou, Lamb, Lichti, MacGibbon, Mereghetti, Mereghetti, Mukherjee, Norris, Norris, Paciesas, Pendleton, Reichart, Ryde, Schmidt, Ubertini, Vedrenne, Winkler   +33 more
core   +1 more source

Detection Techniques of Microsecond Gamma-Ray Bursts using Ground-Based Telescopes [PDF]

, 1999
Gamma-ray observations above 200 MeV are conventionally made by satellite-based detectors. The EGRET detector on the Compton Gamma Ray Observatory (CGRO) has provided good sensitivity for the detection of bursts lasting for more than 200 ms.
Aharonian F. A., Cook A. F., F. Krennrich, Hagedorn R., Hawking S. W., Hawking S. W., Hillas A. M., Porter N. A., S. Le Bohec, T. C. Weekes   +9 more
core   +2 more sources

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

Advanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang, Zhongwei Yang, Yunfan Zhang, Longwei Wang, Xiaoyu Zhang, Jiahui Mao, Yizhi Dai, Yifan Yuan, Mingge Wang, Xin Yang, Xin Yu, Jing Liu, Chunying Chen   +12 more
wiley   +1 more source

Estimating the peak energy of Swift gamma-ray bursts using supervised machine learning

Astronomy & Astrophysics
Gamma-ray bursts (GRBs) are among the most energetic explosive phenomena in the Universe, and their peak energy (Ep) is a key physical quantity for understanding the prompt emission mechanism.
Sun Wan-Peng, Zhu Si-Yuan, Ma Da-Ling, Zhang Fu-Wen   +3 more
doaj   +1 more source

Bright X-ray Flares in Gamma-Ray Burst Afterglows

, 2005
Gamma-ray burst (GRB) afterglows have provided important clues to the nature of these massive explosive events, providing direct information on the nearby environment and indirect information on the central engine that powers the burst.
Angelini, L., Barthelmy, S., Beardmore, A. P., Burrows, D. N., Campana, S., Capalbi, M., Chincarini, G., Cummings, J., Cusumano, G., Falcone, A., Fox, D., Gehrels, N., Giommi, P., Goad, M. R., Hill, J. E., Kennea, J. A., Kobayashi, S., Krimm, H., Mangano, V., Marshall, F., Meszaros, P., Moretti, A., Morris, D. C., Nousek, J. A., O'Brien, P. T., Osborne, J. P., Pagani, C., Page, K. L., Perri, M., Romano, P., Tagliaferri, G., Wells, A. A., Woosley, S., Zhang, B.   +33 more
core   +1 more source

The AUTACE That Degrades KRAS and Engages CD8+ T Cells for the Treatment of KRAS/TP53 Co‐Mutant Tumors

Advanced Science, EarlyView.
AUTACE is a bifunctional nanoplatform that integrates tumor targeting, immune engagement, and on‐demand KRAS degradation. It targets KRAS/TP53 co‐mutant tumors via TP53‐specific TCRs, elicits antitumor CD8+ T‐cell responses through surface anti‐CD3 antibodies, and uses low‐intensity focused ultrasound (LIFU) to trigger controlled release of the KRAS ...
Luo Li, Bolin Li, Yanan Hao, Bo Pang, Pan Li, Chunli Li, Yu Tang   +6 more
wiley   +1 more source

Engineering MnPt Bimetallic Nanozymes for Cascade Enzymatic Therapy and Enhanced Radio‐Immunotherapy

Advanced Science, EarlyView.
A CD44‐targeted MnPt bimetallic nanozyme (HD@MnO2) integrates multienzyme‐like activity with cGAS–STING activation to boost radio‐immunotherapy. Through cascade biocatalysis, it depletes glutathione, relieves hypoxia, and amplifies ROS, enhancing radiotherapy‐induced DNA damage and immunogenic cell death. The nanozyme promotes dendritic cell maturation
Wenyi Zhang, Yangyang Guo, Guoping Xu, Luhaoxiang Liu, Lin Chen, Cai Zhang, Yiming Li, Jianmin Li, Yang Zhao   +8 more
wiley   +1 more source

Profiling Localized Immunomodulation and Drug Biodistribution within a Subcutaneous Vascularized Niche for Cell Transplantation

Advanced Science, EarlyView.
We studied how five common immunosuppressants behave when delivered directly to a transplant site instead of systemically. Using a vascularized implant for islet transplantation, we show that local delivery protects grafts, limits drug spread to the rest of the body, and produces distinct immune signatures.
Jocelyn Nikita Campa‐Carranza, Simone Capuani, Melissa A. Willman, Alexander Rabassa, Ashley L. Joubert, Tommaso Bo, Letizia Franco, Marzia Conte, Ana L. Anaya‐García, Gabrielle E. Rome, Rim Ouni, Henry J. Seaborne, Camden A. Caffey, Dora M. Berman, Junjun Zheng, Jesus Paez‐Mayorga, Corrine Ying Xuan Chua, Shu Hsia Chen, Norma S. Kenyon, Alessandro Grattoni   +19 more
wiley   +1 more source

EXTRAGALACTIC GAMMA-RAYS: GAMMA RAY BURSTS AND BLAZARS

International Journal of Modern Physics A, 2005
The extragalactic gamma-ray sky is dominated by two classes of sources: Gamma-Ray Bursts (GRBs) and radio loud active galactic nuclei whose jets are pointing at us (blazars). We believe that the radiation we receive from them originates from the transformation of bulk relativistic energy into random energy.
openaire   +2 more sources

Lipoic Acid‐Intervened Decellularized Stem Cell Spheroid‐Based Injectable Granular Gel for Diabetic Tissue Regeneration

Advanced Science, EarlyView.
ABSTRACT Advancements in tissue engineering have revolutionized therapeutic paradigms for diabetic tissue defects; however, the lack of applicable scaffold containing various bioactive substance aggregates remained a critical bottleneck hindering satisfactory repair effect.
Tao Wang, Haowei Fang, Lili Qi, Song Myoungseop, Aawrish Khan, Lunli Gong, Guangdong Zhou, Kunxi Zhang, Haiyan Cui   +8 more
wiley   +1 more source