Results 151 to 160 of about 58,726 (292)

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

BMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao, Rui Qu, Zan Dai, Xiqun Jiang, Xu Zhen   +4 more
wiley   +1 more source

Diversity in Fermi/GBM Gamma-Ray Bursts: New Insights from Machine Learning

The Astrophysical Journal
Classification of gamma-ray bursts (GRBs) has been a long-standing puzzle in high-energy astrophysics. Recent observations challenge the traditional short versus long viewpoint, where long GRBs are thought to originate from the collapse of massive stars ...
Dimple, K. Misra, K. G. Arun
doaj   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

BMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu, Xuejian Wang, Wenyan Jiang, Wan Hairul Anuar Kamaruddin, Chunyan Fang, Pengfei Zhang   +5 more
wiley   +1 more source

GRB 221009A and the Apparently Most Energetic Gamma-Ray Bursts

The Astrophysical Journal
Gamma-ray bursts (GRBs) are often referred to as the most luminous explosions in the Universe, due to their short and highly luminous prompt emission.
Jean-Luc Atteia, Laurent Bouchet, Jean-Pascal Dezalay, Francis Fortin, Olivier Godet, Sébastien Guillot, Alain Klotz, Frédéric Daigne, Robert Mochkovitch, Damien Turpin   +9 more
doaj   +1 more source

Gravitational lensing in gamma-ray bursts

Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
Gravitationally lensed gamma-ray bursts (GRBs) offer critical advantages over other lensed sources. They can be detected via continuously operating detectors covering most of the sky. They offer extremely high time resolution to determine lensing delays and find short time delays accurately.
Andrew J. Levan, Benjamin P. Gompertz, Graham P. Smith, Maria Edvige Ravasio, Gavin Lamb, Nial R. Tanvir   +5 more
openaire   +5 more sources

Enhanced strategies for cuproptosis‐like death in bacterial infection treatment

BMEMat, EarlyView.
This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang, Bolong Xu, Ruiyuan Zhu, Hengshuo Gui, Tian Xia, Shaokai Liu, Huiyu Liu, Xianwen Wang   +7 more
wiley   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

Pulse-resolved Classification and Characteristics of Long-duration Gamma-Ray Bursts with Swift-BAT Data. I. Precursors versus Main Bursts

The Astrophysical Journal Supplement Series
Many long gamma-ray bursts (GRBs) exhibit complex prompt emission structures with multiple temporally distinct episodes, such as early-time precursors preceding the main burst. Whether these subcomponents share the same physical origin and classification
Liang Li, Yu Wang, Jin-Jun Geng, Yong-Feng Huang, Rong-Gen Cai   +4 more
doaj   +1 more source

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

BMEMat, EarlyView.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang, Yu‐zhu Wang, Yi‐fei Wang, Que Bai, Jia‐xin Hao, Zhi‐ting Li, Xiao‐qing Cao, Yu Wei, Yue Feng, Ji‐hua Chen, Franklin R. Tay, Rui‐bing Wang, Jun‐ting Gu, Li‐na Niu   +13 more
wiley   +1 more source

Advancing the Classification of Gamma-Ray Bursts Using Machine Learning. I. Gamma-Ray Bursts with Extended Emission

The Astrophysical Journal
Gamma-ray bursts (GRBs) with extended emission (EE) challenge traditional GRB classification schemes, yet their origins remain unknown. In this paper, we employ unsupervised machine learning methods to classify Swift EE GRBs using multidimensional ...
Xiu-Juan Li, Jia-Mu Liu, Zhi-Bin Zhang, Yan-Na Wang, Yuan-Yuan Li   +4 more
doaj   +1 more source