Results 191 to 200 of about 243,781 (346)

Immunomodulatory Nanozymes Eradicate Intracellular Infections and Rescue Immunoparalysis for Treating Multidrug‐Resistant Bacterial Sepsis

open access: yesExploration, EarlyView.
Immunomodulatory nanozymes enable in situ macrophages engineering and orchestrate systemic innate‐adaptive immune response to eradicate intracellular bacteria and rescue immunoparalysis for treating multidrug‐resistant bacterial sepsis. ABSTRACT Sepsis and their sequelae are the leading causes of death in intensive care units, with limited therapeutic ...
Xuancheng Du   +19 more
wiley   +1 more source

A Detailed Time-resolved and Energy-resolved Spectro-polarimetric Study of Bright Gamma-Ray Bursts Detected by AstroSat CZTI in Its First Year of Operation

open access: yesThe Astrophysical Journal
The radiation mechanism underlying the prompt emission remains unresolved and can be resolved using a systematic and uniform time-resolved spectro-polarimetric study. In this paper, we investigated the spectral, temporal, and polarimetric characteristics
Rahul Gupta   +13 more
doaj   +1 more source

Practical Applications of Secondary/Extractive Electrospray Ionization (SESI): A Versatile Tool for Real‐Time Chemical Analysis

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT In the 1980s, researchers discovered the remarkable ability of electrospray plumes to effectively ionize gas‐phase molecules via secondary ionization. Around 20 years later—coinciding with the ambient mass spectrometry revolution—secondary electrospray ionization (SESI) and extractive electrospray ionization (EESI) coupled to mass spectrometry
Xin Luo   +5 more
wiley   +1 more source

Expansion and Spectral Softening of the Dust-scattering Rings of GRB 221009A

open access: yesThe Astrophysical Journal
An expanding X-ray halo or rings appear when short pulses of X-ray radiation from a background source are scattered by clouds of dust in the Milky Way. We study the X-ray rings of the brightest gamma-ray burst (GRB) 221009A, detected by the Swift X-Ray ...
Guoying Zhao, Rong-Feng Shen
doaj   +1 more source

The Quinoline Photoremovable Group (PPG) Platform—A Medicinal Chemist's Approach for Photocage Development and Applications

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Photoremovable protecting groups (PPGs) offer a straightforward solution for the temporary inactivation of biologically active substrates and their subsequent controlled release by light irradiation. Their relatively easy design and mode of application have made them useful tools for studying dynamic biological processes in vitro and in vivo ...
Bence Kontra   +3 more
wiley   +1 more source

Molecular Tools to Study and Control Dopaminergic Neurotransmission With Light

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Dopaminergic neurotransmission is involved in several important brain functions, such as motor control, learning, reward‐motivated behavior, and emotions. Dysfunctions of dopaminergic system may lead to the development of various neurological and psychiatric disorders, like Parkinson's disease, schizophrenia, depression, and addictions ...
Galyna Maleeva   +5 more
wiley   +1 more source

Two Types of q$$ q $$‐Gaussian Distributions Used to Study the Diffusion in a Finite Region

open access: yesMathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT In this work, we explore both the ordinary q$$ q $$‐Gaussian distribution and a new one defined here, determining both their mean and variance, and we use them to construct solutions of the q$$ q $$‐deformed diffusion differential equation. This approach allows us to realize that the standard deviation of the distribution must be a function of
Won Sang Chung   +3 more
wiley   +1 more source

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