Results 41 to 50 of about 5,582,399 (288)

The Upcoming GAMMA-400 Experiment

Universe, 2023
The upcoming GAMMA-400 experiment will be implemented aboard the Russian astrophysical space observatory, which will be operating in a highly elliptical orbit over a period of 7 years to provide new data on gamma-ray emissions and cosmic-ray electron ...
Sergey I. Suchkov, Irina V. Arkhangelskaja, Andrey I. Arkhangelskiy, Aleksey V. Bakaldin, Irina V. Chernysheva, Arkady M. Galper, Oleg D. Dalkarov, Andrey E. Egorov, Maxim D. Kheymits, Mikhail G. Korotkov, Aleksey A. Leonov, Svetlana A. Leonova, Alexandr G. Malinin, Vladimir V. Mikhailov, Pavel Yu Minaev, Nikolay Yu. Pappe, Mikhail V. Razumeyko, Nikolay P. Topchiev, Yuri T. Yurkin   +18 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Gamma-Ray Emission from the S147 Region: Indication of Escaping Cosmic Rays Interacting with Molecular Clouds

The Astrophysical Journal
We present a detailed analysis of γ -ray emission from the middle-aged supernova remnant (SNR) S147 (G180.0−1.7) using approximately 16.5 yr of Fermi-LAT data.
Huan Yang, Bing Liu, Houdun Zeng, Xiaoyuan Huang   +3 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

New stage in high-energy gamma-ray studies with GAMMA-400 after Fermi-LAT

EPJ Web of Conferences, 2017
Fermi-LAT has made a significant contribution to the study of high-energy gamma-ray diffuse emission and the observations of 3000 discrete sources. However, one third of all gamma-ray sources (both galactic and extragalactic) are unidentified, the data ...
Topchiev N.P., Galper A.M., Bonvicini V., Adriani O., Arkhangelskaja I.V., Arkhangelskiy A.I., Bakaldin A.V., Bobkov S.G., Boezio M., Dalkarov O.D., Egorov A.E., Gorbunov M.S., Gusakov Yu.V., Hnatyk B.I., Kadilin V.V., Kaplin V.A., Kheymits M.D., Korepanov V.E., Leonov A.A., Longo F., Mikhailov V.V., Mocchiutti E., Moiseev A.A., Moskalenko I.V., Naumov P.Yu., Picozza P., Runtso M.F., Serdin O.V., Sparvoli R., Spillantini P., Stozhkov Yu.I., Suchkov S.I., Taraskin A.A., Tavani M., Yurkin Yu.T., Zverev V.G.   +35 more
doaj   +2 more sources

The Jet Opening Angle and Event Rate Distributions of Short Gamma-Ray Bursts from Late-time X-Ray Afterglows

The Astrophysical Journal, 2023
We present a comprehensive study of 29 short gamma-ray bursts (SGRBs) observed ≈0.8−60 days postburst using Chandra and XMM-Newton. We provide the inferred distributions of the SGRB jet opening angles and true event rates to compare against neutron star ...
A. Rouco Escorial, W. Fong, E. Berger, T. Laskar, R. Margutti, G. Schroeder, J. C. Rastinejad, D. Cornish, S. Popp, M. Lally, A. E. Nugent, K. Paterson, B. D. Metzger, R. Chornock, K. Alexander, Y. Cendes, T. Eftekhari   +16 more
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Redshift Identifiability from Gamma-Ray Burst Prompt Emission

The Astrophysical Journal
We examine which prompt-emission observables of gamma-ray bursts carry identifiable redshift information in realistic structured-jet scenarios. By examining the photon-level Lorentz and cosmological transformations, we demonstrate that any spectral ...
Shu-Xu Yi
doaj   +1 more source

Chapter 2 Galactic Gamma-ray Sources *

Chinese Physics C, 2022
Abstract In the γ-ray sky, the highest fluxes come from Galactic sources: supernova remnants (SNRs), pulsars and pulsar wind nebulae, star forming regions, binaries and micro-quasars, giant molecular clouds, Galactic center, and the large extended area around the Galactic plane.
Chen, Yang, Bi, Xiao-Jun, Fang, Kun, Guo, Yi-Qing, Liu, Ye, Tam, P.H. Thomas, Vernetto, S., Wang, Zhong-Xiang, Yang, Rui-Zhi, Zhang, Xiao   +9 more
openaire   +1 more source

A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions

Advanced Engineering Materials, EarlyView.
This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice, Krzysztof S. Stopka, Michael D. Sangid   +2 more
wiley   +1 more source