Results 201 to 210 of about 5,722 (281)

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source

Probing the out-of-equilibrium dynamics of driven colloids by X-ray photon correlation spectroscopy. [PDF]

J Appl Crystallogr
Narayanan T, Chèvremont W, Zinn T.
europepmc   +1 more source

Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors

Advanced Science, EarlyView.
This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su, Tianqing Nie, Guofeng Chen, Muya Xiong, Yumin Zhang, Guoqing Wu, Mengyuan You, Hang Xie, Jian He, Yanchao Xiong, Hangchen Hu, Wenfeng Zhao, Minjun Li, Gengfu Xiao, Leike Zhang, Yechun Xu   +15 more
wiley   +1 more source

Predicting spiking activity from scalp EEG. [PDF]

J Neural Eng
Sharma D, Krekelberg B.
europepmc   +1 more source

Explicit Compression Degradation Estimations for Low‐Sampling Single‐Pixel Imaging using Hadamard Basis

Advanced Science, EarlyView.
This study proposes a degradation estimation technique to explicitly describe compressive sampling for low‐sampling Hadamard single‐pixel imaging. Blur kernels in explicit degradation models are estimated by the self‐supervised learning method without labeled data and implicit priors.
Haoyu Zhang, Jie Cao, Chang Zhou, Haifeng Yao, Qun Hao   +4 more
wiley   +1 more source

Performance studies of an ultrafast gamma Cherenkov imaging Screen based on Silica fibers array. [PDF]

Heliyon
Mei Z, Li Y, Song Y, Sheng L, Guo Q, Yan YH, Yin HQ.   +6 more
europepmc   +1 more source

Commissioning of the first CTA large size telescope and study of transient gamma-ray sources

, 2019
Q. Piel
openalex   +1 more source

4D Printing of Magnetically Responsive Shape Memory Polymers: Toward Sustainable Solutions in Soft Robotics, Wearables, and Biomedical Devices

Advanced Science, EarlyView.
Merging 4D printing with magneto‐responsive shape memory polymers opens new avenues for intelligent, reconfigurable systems. This review navigates cutting‐edge fabrication techniques, magnetic fillers, and smart polymer matrices, unveiling their potential in soft robotics, biomedical devices, and wearable tech.
Kiandokht Mirasadi, Mohammad Amin Yousefi, Liuchao Jin, Davood Rahmatabadi, Majid Baniassadi, Wei‐Hsin Liao, Mahdi Bodaghi, Mostafa Baghani   +7 more
wiley   +1 more source

Evaluation of Daughter Radionuclide Release from the ¹⁰³Pd/^103mRh In Vivo Generator for Targeted Auger Therapy. [PDF]

Pharmaceuticals (Basel)
Laouameria AN, Driver CHS, Buys M, Kurakina ES, Hunyadi M, Zeevaart JR, Szucs Z.   +6 more
europepmc   +1 more source

DualPG‐DTA: A Large Language Model‐Powered Graph Neural Network Framework for Enhanced Drug‐Target Affinity Prediction and Discovery of Novel CDK9 Inhibitors Exhibiting in Vivo Anti‐Leukemia Activity

Advanced Science, EarlyView.
This study introduces DualPG‐DTA, a framework integrating two pre‐trained models to generate molecular and protein representations. It constructs dual graphs processed by specialized neural networks with dynamic attention for feature fusion, achieving superior benchmark performance.
Yihao Chen, Jindi Huang, Cong Liu, Shipeng Zhang, Xinze Li, Zhang Zhang, Tie‐Gen Chen, Ling Wang   +7 more
wiley   +1 more source