Results 51 to 60 of about 202,938 (348)

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Search for Joint Multimessenger Signals from Potential Galactic Cosmic-Ray Accelerators with HAWC and IceCube

open access: yesThe Astrophysical Journal
The origin of high-energy galactic cosmic rays is yet to be understood, but some galactic cosmic-ray accelerators can accelerate cosmic rays up to PeV energies.
R. Alfaro   +495 more
doaj   +1 more source

The response of monoenergetic gamma rays in finite media are investigated [PDF]

open access: yes, 1969
In a study of the transport of radiation in matter, the response parameters of monoenergetic gamma rays incident on various materials with finite geometries were calculated on a CDC 3600 computer.
Snow, W. J.
core   +1 more source

On the possibility of sub-TeV Gamma-ray emission from Cyg X-3

open access: yes, 2010
The compact X-ray binary system Cyg X-3 has been recently discovered as a source of GeV gamma-rays by the AGILE and the {\it Fermi} satellites. It shows emission features in the GeV gamma-rays similar to other gamma-ray binaries which were also observed ...
Abdo   +36 more
core   +1 more source

Clues from the prompt emission of GRB 080319B [PDF]

open access: yes, 2008
The extremely bright optical flash that accompanied GRB 080319B suggested, at first glance, that the prompt $\gamma$-rays in this burst were produced by Synchrotron self Compton (SSC). We analyze here the observed optical and $\gamma$ spectrum.
Boër   +16 more
core   +2 more sources

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Are Electrons Oscillating Photons, Oscillating “Vacuum," or Something Else? The 2015 Panel Discussion: An Unprecedented Engineering Opportunity: A Dynamical Linear Theory of Energy as Light and Matter [PDF]

open access: yes, 2015
Platform: What physical attributes separate EM waves, of the enormous band of radio to visible to x-ray, from the high energy narrow band of gamma-ray? From radio to visible to x-ray, telescopes are designed based upon the optical imaging theory; which ...
Akins, Charles G.   +8 more
core   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Gamma-Rays from Intergalactic Shocks [PDF]

open access: yes, 2002
Structure formation in the intergalactic medium (IGM) produces large-scale, collisionless shock waves, where electrons can accelerate to highly relativistic energies.
Hernquist, Lars   +4 more
core   +4 more sources

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

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