Results 81 to 90 of about 6,984,846 (349)

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

The Odd Gamma Weibull-Geometric Model: Theory and Applications

Mathematics, 2019
In this paper, we study a new four-parameter distribution called the odd gamma Weibull-geometric distribution. Having the qualities suggested by its name, the new distribution is a special member of the odd-gamma-G family of distributions, defined with ...
Rana Muhammad Imran Arshad, Christophe Chesneau, Farrukh Jamal   +2 more
doaj   +1 more source

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

Simulação da precipitação diária para Parnaíba e Teresina, PI, em planilha eletrônica Daily rainfall simulation in Parnaíba and Teresina - Brazil, using a spreadsheet

Revista Brasileira de Engenharia Agrícola e Ambiental, 2001
Os estudos envolvendo precipitação pluviométrica são bastante dificultados devido ao fato das séries históricas disponíveis serem, na maioria dos casos, muito pequenas para efetuá-los.
Aderson S. de Andrade Júnior, José A. Frizzone, Paulo C. Sentelhas   +2 more
doaj   +1 more source

Clinical Characteristics and Outcomes of Early‐Onset Versus Late‐Onset LGI1‐Antibody Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Leucine‐rich glioma‐inactivated 1 antibody (LGI1‐Ab) encephalitis predominantly affected older individuals, but has also been reported in younger patients. However, the demographic, clinical, and prognostic characteristics of early‐onset LGI1‐Ab encephalitis have yet to be systematically elucidated. This study aims to systematically
Yu Kong, Shasha Yu, Jing Zhang, Yu Zu, Yujing Zhang, Jing Lv, Xuyang Cao, Xuedan Feng   +7 more
wiley   +1 more source

Domain Specific Placebo Response in the Modified Friedreich's Ataxia Rating Scale

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The placebo response in clinical trials in ataxias complicates outcome interpretation and potentially obscures genuine treatment effects. We analyzed placebo group data from past trials in Friedreich Ataxia and observed notable responses in appendicular items, in contrast to minimal changes in axial function, as measured by respective ...
Christian Rummey, Jennifer M. Farmer, David R. Lynch   +2 more
wiley   +1 more source

A Versatile Distribution Based on the Incomplete Gamma Function: Characterization and Applications

Mathematics
In this study, we introduce a novel distribution related to the gamma distribution, referred to as the generalized incomplete gamma distribution. This new family is defined through a stochastic representation involving a linear transformation of a random
Jimmy Reyes, Carolina Marchant, Karol I. Santoro, Yuri A. Iriarte   +3 more
doaj   +1 more source

Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo, Deyou Peng, Zhouao Zhang, Mingjin Yang, Xinyan Guo, Tianyu Ma, Xiaoyu Huang, Mingming Xu, Linlin Fu, Yong Zhang   +9 more
wiley   +1 more source

Bayesian Methods for Step-Stress Accelerated Test under Gamma Distribution with a Useful Reparametrization and an Industrial Data Application

Mathematics
This paper presents a multiple step-stress accelerated life test using type II censoring. Assuming that the lifetimes of the test item follow the gamma distribution, the maximum likelihood estimation and Bayesian approaches are used to estimate the ...
Hassan S. Bakouch, Fernando A. Moala, Shuhrah Alghamdi, Olayan Albalawi   +3 more
doaj   +1 more source

Tight bounds for the median of a gamma distribution. [PDF]

PLoS One, 2023
Lyon RF.
europepmc   +1 more source