Results 91 to 100 of about 611,363 (262)

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

open access: yesFEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey   +4 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

On the Application of a Hypergeometric Identity to Generate Generalized Hypergeometric Reduction Formulas

open access: yesAxioms
We systematically exploit a new generalized hypergeometric identity to obtain new hypergeometric summation formulas. As a consistency test, alternative proofs for some special cases are also provided.
Juan Luis González-Santander
doaj   +1 more source

Bounds for triple gamma functions and their ratios

open access: yesJournal of Inequalities and Applications, 2016
In this work, in addition to the bounds for triple gamma function, bounds for the ratios of triple gamma functions are obtained. Similar bounds for the ratios of the double gamma functions are also obtained.
Sourav Das, A Swaminathan
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Some special functions and cylindrical diffusion equation on α-time scale

open access: yesDemonstratio Mathematica
This article is dedicated to present various concepts on α\alpha -time scale, including power series, Taylor series, binomial series, exponential function, gamma function, and Bessel functions of the first kind.
Silindir Burcu   +3 more
doaj   +1 more source

Adjoint Bernoulli’s Kantorovich–Schurer-Type Operators: Univariate Approximations in Functional Spaces

open access: yesMathematics
In this work, we first establish a new connection between adjoint Bernoulli’s polynomials and gamma function as a new sequence of linear positive operators denoted by Sr,ς,λ(.;.).
Harun Çiçek   +3 more
doaj   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Exploring new types of Hardy-Hilbert integral inequalities

open access: yesE-Journal of Analysis and Applied Mathematics
This article explores two new types of Hardy-Hilbert integral inequalities constructed using flexible kernel functions. These functions are versatile due to the interplay of two or more parameters, as well as their asymmetric structural properties.
Christophe Chesneau
doaj   +1 more source

Home - About - Disclaimer - Privacy