Results 61 to 70 of about 607,360 (246)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Generalized Bivariate Kummer-Beta Distribution
Ingeniería y Ciencia, 2020 A new bivariate beta distribution based on the Humbert’s confluent hypergeometric function of the second kind is introduced. Various representations are derived for its product moments, marginal densities, marginal moments, conditional densities and ...
Daya K. Nagar +2 more
doaj +1 more source
GAMMA FACTORS IN FUNCTIONAL EQUATIONS [PDF]
Proceedings of the National Academy of Sciences, 1956 This paper is dedicated to Professor Alexander Petrunkevitch on his eightieth birthday. ntribution from the Osborn Zoological Laboratory, Yale University, New Haven, Connecticut. t Theresa Seessel fellow, Yale University, from the University of Vienna. F. A.
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Parameterized Finite Binomial Sums
MathematicsWe offer intriguing new insights into parameterized finite binomial sums, revealing elegant identities such as ∑k=0,k≠nm+n(−1)kn−km+nk=(−1)nm+nn(Hm−Hn), where n,m are non-negative integers and Hn is the harmonic number. These formulas beautifully capture
Necdet Batır, Junesang Choi
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Taylor’s power law for the
Modern Stochastics: Theory and Applications, 2019 Taylor’s power law states that the variance function decays as a power law. It is observed for population densities of species in ecology. For random networks another power law, that is, the power law degree distribution is widely studied.
István Fazekas +2 more
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
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Slightly \gamma-Continuous Functions
Boletim da Sociedade Paranaense de Matemática, 2009 The purpose of this paper is to give a new weak form of some typesof continuity generalizing strongly alpha-irresoluteness, alpha-irresoluteness, alpha-continuity, precontinuity, semi-continuity, gamma-continuity and slightly continuity. In this paper, slightly gama-continuity is introduced and studied.
EKİCİ, ERDAL, Caldas, M.
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source