Results 61 to 70 of about 611,007 (264)
On the definition of the Euler Gamma function
We present a new definition of the Euler Gamma function. From the complex analysis and transalgebraic viewpoint, it is a natural characterization in the space of finite order meromorphic functions. We show how the classical theory and formulas develop naturally, and we discuss the relation with other definitions.
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
GAMMA FACTORS IN FUNCTIONAL EQUATIONS [PDF]
This paper is dedicated to Professor Alexander Petrunkevitch on his eightieth birthday. ntribution from the Osborn Zoological Laboratory, Yale University, New Haven, Connecticut. t Theresa Seessel fellow, Yale University, from the University of Vienna. F. A.
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
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Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Parameterized Finite Binomial Sums
We offer intriguing new insights into parameterized finite binomial sums, revealing elegant identities such as ∑k=0,k≠nm+n(−1)kn−km+nk=(−1)nm+nn(Hm−Hn), where n,m are non-negative integers and Hn is the harmonic number. These formulas beautifully capture
Necdet Batır, Junesang Choi
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Slightly \gamma-Continuous Functions
The purpose of this paper is to give a new weak form of some typesof continuity generalizing strongly alpha-irresoluteness, alpha-irresoluteness, alpha-continuity, precontinuity, semi-continuity, gamma-continuity and slightly continuity. In this paper, slightly gama-continuity is introduced and studied.
EKİCİ, ERDAL, Caldas, M.
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Taylor’s power law for the
Taylor’s power law states that the variance function decays as a power law. It is observed for population densities of species in ecology. For random networks another power law, that is, the power law degree distribution is widely studied.
István Fazekas +2 more
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