Results 31 to 40 of about 902,823 (249)

Immunomodulatory properties and molecular effects in inflammatory diseases of low-dose X-irradiation [PDF]

, 2012
Inflammatory diseases are the result of complex and pathologically unbalanced multicellular interactions. For decades, low-dose X-irradiation therapy (LD-RT) has been clinically documented to exert an anti-inflammatory effect on benign diseases and ...
Seegenschmiedt, Michael H., Keilholz, Ludwig, Stephanie Hehlgans, M. Heinrich eSeegenschmiedt, Guido Hildebrandt, Gaipl, Udo Sebastian, Udo S. Gaipl, Rödel, Franz, Hehlgans, Stephanie, Udo S Gaipl, Manda, Katrin, Ludwig eKeilholz, M. Heinrich Seegenschmiedt, Guido eHildebrandt, Hildebrandt, Guido, Benjamin eFrey, Franz eRödel, Ludwig Keilholz, Frey, Benjamin, Benjamin Frey, Rödel, Claus, Katrin Manda, Claus Rödel, Stephanie eHehlgans, Franz Rödel, Claus eRödel, Katrin eManda   +26 more
core   +1 more source

Effects of gamma irradiation on germination and physiological parameters of maize (Zea mays) genotypes

The Indian Journal of Agricultural Sciences, 2015
This study determined the effect of gamma irradiation on the seedling growth parameters and enzymatic activities of gamma irradiated seeds of two maize (Zea mays L.) genotypes.
ACHCHHELAL YADAV, B SINGH, D K SHARMA, S AHUJA   +3 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Damage Effect of Single and Sequential Neutron/γ Irradiation on Bipolar Device

Yuanzineng kexue jishu
Bipolar transistors are widely used in electronic circuits and serve as core components in various devices. In the complex radiation environments, electronic circuits are exposed to more than one type of radiation particle.
XING Jiabin1, WANG Kai2, CAO Fei1, YANG Jianqun2, QIN Jianqiang1
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Genotoxikus hatásra bekövetkező funkcionális és strukturális DNS változások = Functional and structural changes in DNA upon genotoxic effects [PDF]

, 2008
Morfológiai és biokémiai vizsgálataink arra utalnak, hogy a a genotoxikus hatások kategorizálhatók az okozott kromatin változások alapján. A kemotoxikus változások potenciális diagnosztikus jelentősége miatt vizsgáltuk a nehézfémek (elsősosrban kadmium) (
Szepessy, Edit, Rőszer, Tamás, Bánfalvi, Gáspár, Jenei, Zsolt, Serfőző, Zoltán, Nagy, Gábor György, B. Kiss, Zsigmond   +6 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

The Sensitivity of Leersia hexandra Sw. to Gamma-Ray Irradiation

Journal of Experimental Life Science, 2021
Gamma-ray irradiation as a physical mutagen has high penetrating power. Therefore, it is most often used to increase genetic variability or produce new mutant plants. This research was conducted to obtain the lethal dose of gamma-rays in Leersia hexandra
Pritha Kartika Sukmasari, Wahyu Widoretno, Dian Siswanto   +2 more
doaj   +1 more source

Disinfection of honeybee combs by gamma irradiation II European foul brood disease

, 1970
SummaryCombs from honeybee colonies with European foul brood were exposed to gamma irradiation, up to 0?8 Mrad, but they still contained many cells of Streptococcus pluton and of Bacillus alvei.
Gochnauer, T. A., Pankiw, P., Hamilton, H. A., Bailey, L.   +3 more
core   +1 more source