Results 41 to 50 of about 596,755 (352)

A Roadmap to Gamma-Ray Bursts: New Developments and Applications to Cosmology

Galaxies, 2021
Gamma-ray bursts are the most powerful explosions in the universe and are mainly placed at very large redshifts, up to z≃9. In this short review, we first discuss gamma-ray burst classification and morphological properties.
Orlando Luongo, Marco Muccino
doaj   +1 more source

Probing Orbital Parameters of Gamma-Ray Binaries with TeV Light Curves

The Astrophysical Journal, 2023
Gamma-ray binaries are binary systems in which the energy flux peaks in the gamma-ray energy band. They harbor a compact object (a neutron star or a black hole) orbiting around a massive star, which provides a strong radiation field.
Iurii Sushch, Brian van Soelen
doaj   +1 more source

Gamma-Ray Polarimetry

, 2022
While the scientific potential of high-energy X-ray and gamma-ray polarimetry has long been recognized, measuring the polarization of high-energy photons is challenging. To date, there has been very few significant detections from an astrophysical source.
Bernard, Denis, Chattopadhyay, Tanmoy, Kislat, Fabian, Produit, Nicolas   +3 more
openaire   +2 more sources

Gamma-ray luminosity function of gamma-ray bright AGNs [PDF]

Research in Astronomy and Astrophysics, 2009
Detection of Gamma-ray emission from a class of active galactic nuclei (viz blazars), has been one of the important findings from the Compton Gamma Ray Observatory (CGRO). However, their Gamma-ray luminosity function has not been well determined. Few attempts have been made in earlier works, where BL Lacs and Flat Spectrum Radio Quasars (FSRQs) have ...
Reshmi Mukherjee, Debbijoy Bhattacharya, Debbijoy Bhattacharya, P. Sreekumar   +3 more
openaire   +4 more sources

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

Gamma ray effects on flash memory cell arrays [PDF]

Nuclear Technology and Radiation Protection, 2012
Information stored in flash memories is physically represented by the absence or presence of charge on electrically isolated floating gates. Interaction of gamma rays with the insulators surrounding the floating gate produces effects that degrade the ...
Dolićanin Edin Ć.
doaj   +1 more source

Multi-wavelength Temporal Variability of the Blazar 3C 454.3 during 2014 Activity Phase

, 2016
We present a multi-wavelength temporal analysis of the blazar 3C 454.3 during the high $\gamma$-ray active period from May-December, 2014. Except for X-rays, the period is well sampled at near-infrared (NIR)-optical by the \emph{SMARTS} facility and the ...
Gupta, Alok C., Kushwaha, Pankaj, Misra, Ranjeev, Singh, K. P.   +3 more
core   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Contribution of the Gamma-ray Loud Radio Galaxies Core Emissions to the Cosmic MeV and GeV Gamma-Ray Background Radiation

, 2011
The Fermi gamma-ray satellite has recently detected gamma-ray emissions from radio galaxy cores. From these samples, we first examine the correlation between the luminosities at 5 GHz, L_{5GHz}, and at 0.1-10 GeV, L_{gamma}, of these gamma-ray loud radio
Abdo, Abdo, Abdo, Abdo, Abdo, Abdo, Abdo, Abdo, Abdo, Ajello, Ajello, Atwood, Bennett, Bergström, Bhattacharya, Bhattacharya, Boggs, Burgess, Burgess, Chiang, Dai, Dermer, Dondi, Dunlop, Ekers, Fanaroff, Faucher-Giguère, Fields, Finke, Gruber, Hartman, Hopkins, Horiuchi, Inoue, Inoue, Inoue, Inoue, Kappadath, Kataoka, Kendall, Keshet, Kubo, Laing, Makiya, Massaro, Morganti, Muecke, Murase, Narumoto, Oda, Padovani, Padovani, Pavlidou, Pavlidou, Press, Razzaque, Razzaque, Rybicki, Saikia, Salamon, Siegal-Gaskins, Sreekumar, Stawarz, Stecker, Stecker, Strigari, Strong, Thompson, Thompson, Totani, Totani, Ueda, Unger, Venters, Wang, Watanabe, Watanabe, Yoshiyuki Inoue, Zdziarski, Zhang   +79 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source