Results 51 to 60 of about 610,854 (344)

Gamma-Ray Line Astronomy [PDF]

AIP Conference Proceedings, 2005
9 pages, 5 figures; invited review at "Nuclei in the Cosmos 8", Vancouver, CA; accepted for publication in Nucl Phys ...
openaire   +4 more sources

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Cosmic-Ray Events as Background in Imaging Atmospheric Cherenkov Telescopes

, 2007
The dominant background for observations of gamma-rays in the energy region above 50 GeV with Imaging Atmospheric Cherenkov telescopes are cosmic-ray events.
Aharonian, Aharonian, Aharonian, Bass, Bleicher, G. Maier, Heck, Hillas, Hofmann, J. Knapp, Kalmykov, Knapp, Krawczynski, Schatz, Weekes   +14 more
core   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Compton Dragged Gamma--Ray Bursts associated with Supernovae [PDF]

, 1999
It is proposed that the gamma-ray photons that characterize the prompt emission of Gamma-Ray Bursts are produced through the Compton drag process, caused by the interaction of a relativistic fireball with a very dense soft photon bath.
Annalisa Celotti, Davide Lazzati, Gabriele Ghisellini, Martin J. Rees, Owens A., Shemi A.   +5 more
core   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Extending the Short Gamma-Ray Burst Population from Subthreshold Triggers in Fermi/GBM and GECAM Data and Its Implications

The Astrophysical Journal Letters
Detection of short gamma-ray bursts (SGRBs) is critically important for the research of compact object mergers and multimessenger astrophysics, but a significant part of SGRBs fall below the trigger threshold of GRB detectors, and thus are often missed ...
Ce Cai, Shao-Lin Xiong, Yan-Qiu Zhang, Jin-Peng Zhang, Ping Wang, Yao-Guang Zheng, Shi-Jie Zheng, Shuo Xiao, Hao-Xuan Guo, Jia-Cong Liu, Yang-Zhao Ren, Wen-Jun Tan, Chen-Wei Wang, Yue Wang, Sheng-Lun Xie, Wang-Chen Xue, Zheng-Hang Yu, Peng Zhang, Wen-Long Zhang, Chao Zheng, Jia-Wei Luo, Shuai Zhang, Li-Ming Song, Shuang-Nan Zhang   +23 more
doaj   +1 more source

Prompt gamma-ray methods for industrial process evaluation: A simulation study

Nukleonika, 2022
Radioisotope applications in industrial process inspection and evaluation using gamma-ray emitters provide otherwise unavailable information. Offering alternative gamma-ray sources can support the technology by complementing sources’ availability and ...
Mohammed Mohammed Siddig H., Alhawsawi Abdulsalam, Aljohani M. S., Damoom Mohammed M., Banoqitah Essam M., Elmoujarkach Ezzat   +5 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

The Case of the Missing Very High-energy Gamma-Ray Bursts: A Retrospective Study of Swift Gamma-Ray Bursts with Imaging Atmospheric Cherenkov Telescopes

The Astrophysical Journal
Gamma-ray bursts (GRBs) are particle acceleration sites that can emit photons in the very high-energy (VHE) domain through nonthermal processes. From 2004 until 2018, the current generation of Imaging Atmospheric Cherenkov Telescopes (IACTs) did not ...
H. Ashkar, A. Sangaré, S. Fegan, J. Damascene Mbarubucyeye, E. Ruiz-Velasco, S. J. Zhu   +5 more
doaj   +1 more source