Results 111 to 120 of about 4,044 (208)

Porcine endogenous retroviruses PERV A and A/C recombinant are insensitive to a range of divergent mammalian TRIM5  proteins including human TRIM5 [PDF]

, 2009
The potential risk of cross-species transmission of porcine endogenous retroviruses (PERV) to humans has slowed the development of xenotransplantation, using pigs as organ donors. Here, we show that PERVs are insensitive to restriction by divergent TRIM5{
Anderson, Andrew Wood, Asaoka, Bainbridge, Bartosch, Bartosch, Bartosch, Benjamin L. J. Webb, Berthoux, Besnier, Birke Bartosch, Bock, Greg J. Towers, Hanger, Hatziioannou, Hatziioannou, Hatziioannou, Jonsson, Kaiser, Keckesova, Keckesova, Le Tissier, Lieber, Lin, Martin, Martin, Mortuza, Naviaux, Negre, Neil, Newman, Niebert, Nisole, Oldmixon, Passerini, Patience, Patience, Perez-Caballero, Perron, Rambaut, Sakuma, Schaller, Si, Song, Stoye, Stoye, Stremlau, Stremlau, Stremlau, Takeuchi, Tarlinton, Torsten Schaller, Towers, Towers, Towers, Wilson, Wu, Yap, Yasuhiro Takeuchi, Ylinen, Ylinen, Zufferey   +61 more
core   +2 more sources

Integration of Planova filters in manufacturing processes of biologicals improve the virus safety effectively: A review of publicly available data

Biotechnology Progress, Volume 40, Issue 1, January/February 2024.
Abstract The capacity to remove viruses by Planova filters produced by Asahi Kasei, primarily by small virus‐retentive filters, were compiled from data in peer‐reviewed publications and, partly, publicly available data from presentations at conferences (Planova workshops).
Albrecht Gröner
wiley   +1 more source

Cholesterol depletion inactivates XMRV and leads to viral envelope protein release from virions: evidence for role of cholesterol in XMRV infection. [PDF]

PLoS ONE, 2012
Membrane cholesterol plays an important role in replication of HIV-1 and other retroviruses. Here, we report that the gammaretrovirus XMRV requires cholesterol and lipid rafts for infection and replication.
Yuyang Tang, Alvin George, Thyneice Taylor, James E K Hildreth   +3 more
doaj   +1 more source

Engineering protein self-assembling in protein-based nanomedicines for drug delivery and gene therapy [PDF]

, 2015
Altres ajuts: FISS/PS09-00165Altres ajuts: FISS/PI12-00327Lack of targeting and improper biodistribution are major flaws in current drug-based therapies that prevent reaching high local concentrations of the therapeutic agent.
Corchero Nieto, José Luis, Ferrer-Miralles, Neus, Garcia-Fruitos, Elena, Rodríguez-Carmona, Escarlata, Villaverde Corrales, Antonio, Vázquez Gómez, Esther   +5 more
core   +2 more sources

Occurrence of Typical Domestic Animal Viruses in Wild Carnivorans: An Emerging Threat to the Conservation of Endangered Species

Transboundary and Emerging Diseases, Volume 2024, Issue 1, 2024.
Wild species are susceptible to several typical domestic animal pathogens, and the increasingly close contact between these groups is a predictive factor for disease exposure. Some viruses are important and old‐known, and others are emerging or reemerging for domestic carnivorans and have been identified as threats to the conservation of wild mammals ...
Nathana B. Martins, Julio C. Neves de Almeida, Marianne S. S. Gonçalves, Lana I. Gila, Débora R. Yogui, Mario H. Alves, Arnaud L. J. Desbiez, Paulo E. Brandão, Aline S. da Hora, Walter Lilenbaum   +9 more
wiley   +1 more source

Perinatal Gene Transfer to the Liver [PDF]

, 2011
The liver acts as a host to many functions hence raising the possibility that any one may be compromised by a single gene defect. Inherited or de novo mutations in these genes may result in relatively mild diseases or be so devastating that death within
Buckley, SM, Chan, JK, Howe, SJ, McKay, TR, Rahim, AA, Waddington, SN, Ward, NJ   +6 more
core   +1 more source

The gammaretroviral p12 protein has multiple domains that function during the early stages of replication. [PDF]

, 2012
BACKGROUND: The Moloney murine leukaemia virus (Mo-MLV) gag gene encodes three main structural proteins, matrix, capsid and nucleocapsid and a protein called p12.
Allen, David J, Bishop, Kate N, Boucherit, Virginie C, Nader, Mirella, Taylor, Ian A, Wight, Darren J   +5 more
core   +2 more sources

Effects of reticuloendotheliosis virus infection on cytokine production in SPF chickens. [PDF]

PLoS ONE, 2013
Infection with reticuloendotheliosis virus (REV), a gammaretrovirus in the Retroviridae family, can result in immunosuppression and subsequent increased susceptibility to secondary infections.
Mei Xue, Xingming Shi, Yan Zhao, Hongyu Cui, Shunlei Hu, Xianlan Cui, Yunfeng Wang   +6 more
doaj   +1 more source

Vírus da leucemia felina: análise da classificação da infecção, das técnicas de diagnóstico e da eficácia da vacinação com o emprego de técnicas sensíveis de detecção viral Feline leukemia virus: infection outcomes, diagnostic techniques and vaccine efficacy analysis employing sensitive techniques of virus detection

Ciência Rural, 2011
O Vírus da leucemia felina (FeLV) pertence à família Retroviridae, gênero Gammaretrovirus. Diferentemente de outras retroviroses, uma parcela dos gatos jovens e adultos exposta ao FeLV não apresenta antigenemia/viremia, de acordo com as técnicas ...
Andreza Soriano Figueiredo, João Pessoa Araújo Júnior   +1 more
doaj   +1 more source

Mining metagenomes and metatranscriptomes unveils viruses associated with cutaneous squamous cell carcinoma in hematopoietic stem cell transplant recipients

Microbiology Spectrum
We investigated the presence of viral DNA and RNA in cutaneous squamous cell carcinoma (cSCC) tumor and normal tissues from nine individuals with a history of hematopoietic stem cell transplantation (HCT).
Jana K. Dickter, Yuqi Zhao, Vishwas Parekh, Huiyan Ma, Badri G. Modi, Wai-Yee Li, Saro H. Armenian, Xiwei Wu, Farah R. Abdulla   +8 more
doaj   +1 more source