Suche nach der Ursache des chronischen Erschöpfungssyndroms: Eine Geschichte mit Fortsetzung [PDF]
Zusammenfassung: Die Ursache des chronischen Erschöpfungssyndroms ist Gegenstand einer durchaus engagierten Debatte zwischen Wissenschaft, Behandlern, betroffenen Patienten und Selbsthilfegruppen, deren Form und Intensität nicht nur durch die Inhalte der
Gaab, Jens
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CAR-T cell. the long and winding road to solid tumors [PDF]
Adoptive cell therapy of solid tumors with reprogrammed T cells can be considered the "next generation" of cancer hallmarks. CAR-T cells fail to be as effective as in liquid tumors for the inability to reach and survive in the microenvironment ...
A Heczey +106 more
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In 2009, Lombardi et al. reported their startling finding that the gammaretrovirus xenotropic murine leukemia virus-related retrovirus (XMRV) is present in 67% of blood samples of patients suffering from chronic fatigue syndrome (CFS), as opposed to only
Brendan Oakes +4 more
doaj +1 more source
HERV-H RNA is abundant in human embryonic stem cells and a precise marker for pluripotency [PDF]
BACKGROUND: Certain post-translational modifications to histones, including H3K4me3, as well as binding sites for the transcription factor STAT1, predict the site of integration of exogenous gamma-retroviruses with great accuracy and cell-type ...
Federico A Santoni +2 more
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No evidence of xenotropic murine leukemia virus-related virus transmission by blood transfusion from infected rhesus macaques [PDF]
The discovery of xenotropic murine leukemia virus-related virus (XMRV) in human tissue samples has been shown to be due to virus contamination with a recombinant murine retrovirus.
Galvin, Teresa A +5 more
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The base excision repair pathway is required for efficient lentivirus integration.
An siRNA screen has identified several proteins throughout the base excision repair (BER) pathway of oxidative DNA damage as important for efficient HIV infection.
Kristine E Yoder +8 more
doaj +1 more source
Molecular mechanisms of retroviral integration site selection [PDF]
Retroviral replication proceeds through an obligate integrated DNA provirus, making retroviral vectors attractive vehicles for human gene-therapy. Though most of the host cell genome is available for integration, the process of integration site selection
Engelman, Alan +4 more
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Prevalencia y factores de riesgo de Leucemia Felina en gatos domésticos del municipio de Quinchía. (2017-2018) [PDF]
La leucemia felina (FeLV) es un retrovirus de la familia Gammaretrovirus que puede afectar a gatos domésticos y a otros felinos, los virus que más afectan a nuestros felinos son el sida Felino (FIV), FeLv y virus oncogénicos.
Calvo Gutiérrez, Camila de Jesús +1 more
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Probing the viral replication of HCV and XMRV : biochemical characterization, inhibition kinetics and role of host proteins in viral replication [PDF]
The studies described in this thesis focus on RNA viruses XMRV and HCV. In Chapter II we focused on Xenotropic Murine leukemia-Related Virus (XMRV). We characterized the biochemical activity and kinetics of the XMRV reverse transcriptase and discovered ...
Ndongwe, Tanyaradzwa P.
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Fibronectin-binding nanoparticles for intracellular targeting addressed by B. burgdorferi BBK32 protein fragments [PDF]
Virus-like particles (VLPs) are created by the self-assembly of multiple copies of envelope and/or capsid proteins from many viruses, mimicking the conformation of a native virus.
Akopjana, Inara +10 more
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