Results 121 to 130 of about 4,044 (208)

Suche nach der Ursache des chronischen Erschöpfungssyndroms: Eine Geschichte mit Fortsetzung [PDF]

open access: yes, 2018
Zusammenfassung: Die Ursache des chronischen Erschöpfungssyndroms ist Gegenstand einer durchaus engagierten Debatte zwischen Wissenschaft, Behandlern, betroffenen Patienten und Selbsthilfegruppen, deren Form und Intensität nicht nur durch die Inhalte der
Gaab, Jens
core  

CAR-T cell. the long and winding road to solid tumors [PDF]

open access: yes, 2018
Adoptive cell therapy of solid tumors with reprogrammed T cells can be considered the "next generation" of cancer hallmarks. CAR-T cells fail to be as effective as in liquid tumors for the inability to reach and survive in the microenvironment ...
A Heczey   +106 more
core   +2 more sources

Failure to Detect XMRV-Specific Antibodies in the Plasma of CFS Patients Using Highly Sensitive Chemiluminescence Immunoassays

open access: yesAdvances in Virology, 2011
In 2009, Lombardi et al. reported their startling finding that the gammaretrovirus xenotropic murine leukemia virus-related retrovirus (XMRV) is present in 67% of blood samples of patients suffering from chronic fatigue syndrome (CFS), as opposed to only
Brendan Oakes   +4 more
doaj   +1 more source

HERV-H RNA is abundant in human embryonic stem cells and a precise marker for pluripotency [PDF]

open access: yes, 2012
BACKGROUND: Certain post-translational modifications to histones, including H3K4me3, as well as binding sites for the transcription factor STAT1, predict the site of integration of exogenous gamma-retroviruses with great accuracy and cell-type ...
Federico A Santoni   +2 more
core   +2 more sources

No evidence of xenotropic murine leukemia virus-related virus transmission by blood transfusion from infected rhesus macaques [PDF]

open access: yes, 2012
The discovery of xenotropic murine leukemia virus-related virus (XMRV) in human tissue samples has been shown to be due to virus contamination with a recombinant murine retrovirus.
Galvin, Teresa A   +5 more
core   +2 more sources

The base excision repair pathway is required for efficient lentivirus integration.

open access: yesPLoS ONE, 2011
An siRNA screen has identified several proteins throughout the base excision repair (BER) pathway of oxidative DNA damage as important for efficient HIV infection.
Kristine E Yoder   +8 more
doaj   +1 more source

Molecular mechanisms of retroviral integration site selection [PDF]

open access: yes, 2015
Retroviral replication proceeds through an obligate integrated DNA provirus, making retroviral vectors attractive vehicles for human gene-therapy. Though most of the host cell genome is available for integration, the process of integration site selection
Engelman, Alan   +4 more
core   +1 more source

Prevalencia y factores de riesgo de Leucemia Felina en gatos domésticos del municipio de Quinchía. (2017-2018) [PDF]

open access: yes, 2019
La leucemia felina (FeLV) es un retrovirus de la familia Gammaretrovirus que puede afectar a gatos domésticos y a otros felinos, los virus que más afectan a nuestros felinos son el sida Felino (FIV), FeLv y virus oncogénicos.
Calvo Gutiérrez, Camila de Jesús   +1 more
core  

Probing the viral replication of HCV and XMRV : biochemical characterization, inhibition kinetics and role of host proteins in viral replication [PDF]

open access: yes
The studies described in this thesis focus on RNA viruses XMRV and HCV. In Chapter II we focused on Xenotropic Murine leukemia-Related Virus (XMRV). We characterized the biochemical activity and kinetics of the XMRV reverse transcriptase and discovered ...
Ndongwe, Tanyaradzwa P.
core   +1 more source

Fibronectin-binding nanoparticles for intracellular targeting addressed by B. burgdorferi BBK32 protein fragments [PDF]

open access: yes, 2013
Virus-like particles (VLPs) are created by the self-assembly of multiple copies of envelope and/or capsid proteins from many viruses, mimicking the conformation of a native virus.
Akopjana, Inara   +10 more
core   +1 more source

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