Results 201 to 208 of about 4,044 (208)

The Evolution of Gammaretrovirus Restriction Factors in the Mouse

2010
Mice exposed to infectious retroviruses are subject to virus-induced disease or virus-induced genetic mutations. While mice are protected by the innate and acquired immune systems, they have also evolved numerous constitutively expressed antiviral factors that target various stages of the retroviral life cycle, and these factors have been identified ...
openaire   +1 more source

Re: Identification of a Novel Gammaretrovirus in Prostate Tumors of Patients Homozygous for R462Q RNASEL Variant

European Urology, 2006
Anders Bjartell
openalex   +2 more sources

Unique Integration Profiles of Gammaretrovirus, Lentivirus, and Foamy Virus Transduced Dog Long-Term Repopulating Cells.

Blood, 2006
Abstract Retroviral vectors have been the most effective gene delivery vehicles for hematopoietic stem cell (HSC) gene therapy and patients are now being successfully treated for genetic diseases. Following the success of gene therapy for inherited disorders, such as X-linked severe combined immunodeficiency (SCID), three of the patients
Kirsten A. Keyser, Brian C. Beard, Grant Trobridge, Laura J. Peterson, Dan Miller, Mike Jacobs, Rajinder Kaul, Hans-Peter Kiem   +7 more
openaire   +1 more source

1425 THE HUMAN EXOGENOUS GAMMARETROVIRUS XMRV: PREVALENCE IN PROSTATE CANCER TISSUE AND VIRAL MECHANISMS CONTRIBUTING TO TUMORIGENESIS

Journal of Urology, 2010
Kristin Stieler, Thorsten Schlomm, Andrea Kristina Horst, Claudia Schulz, Hartwig Huland, Martin Aepfelbacher, Nicole Fischer   +6 more
openalex   +2 more sources

Functional Assessment of the Engraftment Potential of Gammaretrovirus-Modified CD34+ Cells, Using a Short Serum-Free Transduction Protocol

Human Gene Therapy, 2006
The successful transduction and engraftment of human mobilized peripheral blood (MBP) CD34(+) cells are determined to a large extent by the ex vivo cell-processing conditions. In preparation for upcoming clinical trials, we investigated essential culture parameters and devised a short and efficient gammaretroviral transduction protocol entailing ...
Tulin, Budak-Alpdogan, Mark, Przybylowski, Mithat, Gonen, Michel, Sadelain, Joseph, Bertino, Isabelle, Rivière   +5 more
openaire   +2 more sources

Unique Integration Profiles in a Canine Model of Long-Term Repopulating Cells Transduced with Gammaretrovirus, Lentivirus, or Foamy Virus

Human Gene Therapy, 2007
B. Beard, K. Keyser, G. Trobridge, L. Peterson, Daniel G. Miller, M. Jacobs, R. Kaul, H. Kiem   +7 more
semanticscholar   +1 more source

Faculty Opinions recommendation of Host range and cellular tropism of the human exogenous gammaretrovirus XMRV.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2010
openaire   +1 more source

Individual pattern of RNA expression of human endogenous gammaretrovirus-like sequences in the human brain

, 2007
Zhihong Yun, Lijuan Hu, Anna Forsman, Dmitrijs Uzhameckis, Patric Jern, Robert H. Yolken, R Fuller Torrey, Jonas Blomberg   +7 more
openalex