Results 191 to 200 of about 290,414 (290)

Transdiagnostic Comparison of Anticipated Hedonic Deficits: A Three‐Level Meta‐Analysis Across Schizophrenia, Depression, and Their Subclinical Individuals

open access: yesPsyCh Journal, Volume 15, Issue 2, April 2026.
ABSTRACT Anhedonia, a transdiagnostic symptom for schizophrenia and depression, exists in subclinical individuals at risk of the two disorders. Prior meta‐analytic reviews seldom considered both anticipated pleasure and anticipated displeasure. We conducted a three‐level meta‐analysis on anticipated pleasure and displeasure in people with schizophrenia
Yan Gao   +4 more
wiley   +1 more source

Antivirals Targeting Coronavirus RNA‐Dependent RNA Polymerase and Main Protease: From Mechanisms of Action to Outcomes in COVID‐19 Clinical Trials

open access: yesMicrobial Biotechnology, Volume 19, Issue 4, April 2026.
The target sites of COVID‐19 antivirals discussed in the present opinion paper, namely the RNA dependent RNA polymerase Nsp12 and of the main viral protease Nsp5, are indicated by a red star in the overview of the replication cycle of coronavirus SARS‐CoV‐2.
Harald Brüssow
wiley   +1 more source

Data‐driven discovery of mechanistic ecosystem models with LLMs

open access: yesMethods in Ecology and Evolution, Volume 17, Issue 4, Page 1303-1321, April 2026.
Abstract Ecosystem models are essential for ecosystem management, but their development traditionally requires significant time and expertise, creating bottlenecks in addressing urgent environmental challenges. We present LEMMA (LLM Enabled Mechanistic Modelling for ecosystem Assessment), a framework that programmatically generates and iteratively ...
Scott Spillias   +6 more
wiley   +1 more source

Health Impacts of Nursing Home Staffing.

open access: yesJAMA Health Forum
Olenski A, Shen K, Ruffini K, Gandhi A.
europepmc   +1 more source

Safety and Efficacy Assessment of Trastuzumab Emtansine in Indian Patients With Human Epidermal Growth Factor Receptor 2‐Positive Unresectable Locally Advanced or Metastatic Breast Cancer Previously Treated With Trastuzumab and a Taxane: An Open‐Label, Single‐Arm, Phase IV Study

open access: yesAsia-Pacific Journal of Clinical Oncology, Volume 22, Issue 2, Page 240-250, April 2026.
A phase IV, single‐arm, open‐label, multicenter study assessing the safety and efficacy of trastuzumab emtansine in Indian patients for the treatment of human epidermal growth factor receptor 2 (HER2)‐positive unresectable locally advanced or metastatic breast cancer who received prior treatment with trastuzumab and a taxane.
Sudeep Gupta   +13 more
wiley   +1 more source

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