Results 71 to 80 of about 402,508 (250)
W Oliver Tobin1, Byron R Spencer2, Bart M Demaerschalk21Department of Neurology, Adelaide and Meath Hospital, Dublin, incorporating the National Children’s Hospital, Ireland; 2Department of Neurology, Mayo Clinic Arizona, USAAbstract: Herpes ...
W Oliver Tobin +2 more
doaj
Functionalized Biomimetic Scaffolds for Human‐Derived Auditory Neural Circuit Construction
In Vitro Auditory Circuit Model. ABSTRACT Damage to auditory circuits results in sensorineural hearing loss. However, the scarcity of human inner ear tissue significantly hinders the development of therapies to preserve auditory function, creating a critical need for reliable in vitro models.
Pan Feng +12 more
wiley +1 more source
The parasympathetic and sensory innervation of the proximal and distal colon in male mice
IntroductionThe distributions of extrinsic neurons innervating the colon show differences in experimental animals from humans, including the vagal and spinal parasympathetic innervation to the distal colon.
Lixin Wang +3 more
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Large‐scale whole‐exome sequencing in 356,982 UK Biobank participants defines the protein‐coding architecture of retinal structure, visual function, and major blinding diseases. Pleiotropic genes, including CFI, C3, and RIOX1, bridge multiple retinal phenotypes, while experimental validation of FYB2 implicates RPE barrier dysfunction, providing ...
Jianqing Li +23 more
wiley +1 more source
Progress of dorsal root ganglia in mechanism of pain
Dorsal root ganglia (DRG) neurons are the primary afferent neurons of algaesthesis of trunk and extremities. DRG transmits and accommodates sensations and accepts and conveys nociception, so it plays an important role in the mechanism of pain.
Jing-zhi LIU
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In this work, we design an ultrasound‐activated piezoelectric hydrogel platform (AOEF@AP5+US) that reprograms neurogenesis‐macrophage crosstalk as an integrated strategy to overcome the intertwined barriers of chronic inflammation, peripheral neuropathy, and impaired regeneration in diabetic wounds.
Kai Wang +13 more
wiley +1 more source
High-resolution imaging and three-dimensional model of the feline spinal cord
The spinal cord is a critical component of the central nervous system, responsible for integrating somatosensory inputs, generating motor outputs, and regulating autonomic functions.
Jonathan Harnie +9 more
doaj +1 more source
Mechanisms of pain processing: spinal protein translation in the rat [PDF]
The word ‘pain’ is described by the International Association for the Study of Pain (IASP) as an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage.
Asante, C O, Asante, C.O.
core
Systematic Multi‐Level Analyses Decode the Arthritis‐Neurodegeneration Axis With In Vivo Validation
Arthritis and neurodegeneration are usually studied as separate disorders, but this study connects them through population evidence, genetic inference, transcriptomic mapping, and mouse models. It highlights RNF40 as a context‐dependent joint‐brain candidate, induced in inflammatory joints yet functionally linked to dopamine‐neuron vulnerability ...
Jinwen Wang +7 more
wiley +1 more source
Electrophysiological characterization of activation state-dependent Cav2 channel antagonist TROX-1 in spinal nerve injured rats. [PDF]
Prialt, a synthetic version of Cav2.2 antagonist ω-conotoxin MVIIA derived from Conus magus, is the first clinically approved voltage-gated calcium channel blocker for refractory chronic pain.
Schiene, K. +17 more
core +1 more source

