Results 11 to 20 of about 1,864 (169)
Differences in macular pigment optical density across four ethnicities: a comparative study
Therapeutic Advances in Ophthalmology, 2020 Objective: The aim of this study is to compare macular pigment optical density levels across four different ethnicities and study its influence on ganglion cell layer and retinal nerve fibre layer thickness across these ethnicities.
Pinakin Gunvant Davey +2 more
doaj +1 more source
Frontiers in Molecular Biosciences, 2022 Although mutations in ADAMTS10 have long been known to cause autosomal recessive Weill-Marchesani Syndrome which is characterized by short stature and ocular abnormalities, more recent work has shown that certain mutations in ADAMTS10 cause glaucoma in ...
Lauren K. Wareham +8 more
doaj +1 more source
Journal of Ophthalmology, 2015 Purpose. To assess the repeatability of spectral-domain optical coherence tomography to measure macular and perimacular ganglion cell complex thicknesses and compare retinal ganglion cell parameters between algorithms. Methods. Ninety-two nonglaucomatous
Dorothy S. K. Ng +6 more
doaj +1 more source
Suppressed retinal degeneration in aged wild type and APPswe/PS1ΔE9 mice by bone marrow transplantation. [PDF]
PLoS ONE, 2013 Alzheimer's disease (AD) is an age-related condition characterized by accumulation of neurotoxic amyloid β peptides (Aβ) in brain and retina. Because bone marrow transplantation (BMT) results in decreased cerebral Aβ in experimental AD, we hypothesized ...
Yue Yang +6 more
doaj +1 more source
Neuronal Nitric Oxide Synthase Is Crucial for Ganglion Cell Death in Rat Retinal Explant Cultures
Journal of Pharmacological Sciences, 2004 We examined possible involvement of nitric oxide synthase (NOS) on ganglion cell death in explant cultures of neonatal rat retina. Survival of retinal ganglion cells was significantly prolonged by a broad-spectrum NOS inhibitor Nω-nitro-L-arginine ...
Hiroshi Katsuki +4 more
doaj +1 more source
Türk Biyokimya Dergisi, 2022 We aimed on evaluating the effect of liver dysfunction on retinal nerve fiber layer (RNFL), GCL++ (ganglion cell layer + RNFL + inner plexiform layer), central macular thickness (CMT) and subfoveal choroidal thickness (CT) measurements.
Zeki Fikret Cenk +5 more
doaj +1 more source
Hyperactivity of ON-type retinal ganglion cells in streptozotocin-induced diabetic mice. [PDF]
PLoS ONE, 2013 Impairment of visual function has been detected in the early stage of diabetes but the underlying neural mechanisms involved are largely unknown.
Jun Yu +5 more
doaj +1 more source
Amyloid-Beta Peptide Is Toxic to Neurons In Vivo via Indirect Mechanisms
Neurobiology of Disease, 2002 We have studied the neurotoxicity of amyloid-beta (Aβ) after a single unilateral intravitreal injection. Within the retina apoptotic cells were seen throughout the photoreceptor layer and the inner nuclear layer but not in the ganglion cell layer at 48 h
Desmond T. Walsh +9 more
doaj +1 more source
Cirrhosis-induced morphological changes in the retina:possible role of endogenous opioid [PDF]
International Journal of Ophthalmology, 2015 AIM:To investigate the impact of cirrhosis on retinal morphology and to evaluate the role of endogenous opioids as a mediator in cirrhosis induced retinal change.METHODS:Thirty-six male rats were divided into 3 main groups; the common bile duct ligated ...
Mohammad Abdullah Algazo +6 more
doaj +1 more source
Therapeutic Advances in Ophthalmology, 2020 Purpose: To identify the peripapillary retinal nerve fiber layer, total macular, ganglion cell layer, and inner plexiform layer thicknesses in children with high hyperopia using spectral domain optical coherence tomography.
Funda Dikkaya, Sevil Karaman Erdur
doaj +1 more source