Results 201 to 210 of about 133,543 (284)

Fine‐needle aspirates and computed tomography assisting in the diagnosis of cholesteatoma in a dog with recurrent otitis

open access: yesVeterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Summary A 10‐year‐old, male, neutered Bichon‐Frisé, with a history of recurrent otitis externa, was presented to a referral centre with sudden‐onset head tilt. Neurological examination was consistent with right peripheral vestibular syndrome and facial neuropathy.
Myrto Spyropoulou   +5 more
wiley   +1 more source

Cytological diagnosis of ganglion cyst in a dog: A case report from a resource-limited setting. [PDF]

open access: yesOpen Vet J
Reynoso ICG   +7 more
europepmc   +1 more source

Gene therapy for hereditary deafness: Progress, challenges and translational implications from OTOF to GJB2

open access: yesClinical and Translational Discovery, Volume 6, Issue 5, October 2026.
Current Management & Limitations: Traditional auditory devices lack genetic curative potential and yield variable, non‐physiological hearing outcomes. OTOF gene therapy has shown promising clinical outcomes with dual‐AAV therapy. GJB2 gene therapy remains an emerging approach with significant translational challenges. Advances in vector design and cell‐
Jiahui Zhao, Mengzhao Xun, Yu Sun
wiley   +1 more source

Mesenchymal Stem Cell‐Derived Extracellular Vesicles Ameliorate NaIO3‐Induced Dry AMD by Delivering miR‐486‐3p to Inhibit Lipocalin‐2‐Mediated Ferroptosis

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Our study reveals a novel mechanism by which MSC‐derived EVs alleviate NaIO3‐induced dry AMD‐like pathology. MSC‐EVs deliver miR‐486‐3p into retinal cells to directly inhibit the ferroptosis‐promoting target gene Lcn2. Concurrently, downregulated Lcn2 restores intracellular Gpx4 expression, thereby suppressing ferroptosis and rescuing retinal ...
Zheng Li   +6 more
wiley   +1 more source

A Sub‐Microsecond Switch Enabling SWIFT 23Na Imaging at 10.5 T

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 4, Page 1991-2003, October 2026.
ABSTRACT PurposeTo enable sodium SWIFT imaging, which is a zero‐echo time imaging technique, at ultra‐high magnetic fields through the development of custom electronics hardware, and to showcase this capability with in vivo imaging results. MethodsThe custom hardware developed consists of a high‐speed optical trigger with 10 ns resolution, an in‐bore ...
Russell L. Lagore   +10 more
wiley   +1 more source

Inhibition of leucine‐rich kinase 2 (LRRK2) promotes peripheral axon regeneration via phosphorylation‐network remodelling

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 20, Page 6199-6224, October 2026.
Background and Purpose In contrast to neurons in the central nervous system, neurons in the peripheral nervous system can regenerate axons after injury via activation of a pro‐regenerative transcriptional programme. Pathogenic mutations in leucine‐rich repeat kinase 2 (LRRK2) are the most common genetic cause of Parkinson's disease, and several small ...
Eun‐Hae Jang   +11 more
wiley   +1 more source

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