Results 61 to 70 of about 3,934 (208)

Keratan Sulfate Is a Multifunctional Brain Glycosaminoglycan With Instructive Capabilities

open access: yesJournal of Neurochemistry, Volume 169, Issue 8, August 2025.
Keratan sulfate (KS) is a multifunctional glycosaminoglycan with fascinating instructional regulatory, tissue organizational, and stabilization properties in the brain. KS has essential properties that regulate neuron proliferation and differentiation with synaptic roles and perineuronal net activities in cognitive activity and memory that define brain
James Melrose
wiley   +1 more source

Tumor de mediastino na criança. [PDF]

open access: yes, 2001
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Pediatria, Curso de Medicina, Florianópolis ...
Damo, Mariana Ferreira
core  

Cancer incidence and stage at diagnosis in children and adolescents in the Community of Madrid, 2015–2018

open access: yesPaediatric and Perinatal Epidemiology, Volume 39, Issue 5, Page 445-455, July 2025.
Abstract Background Cancer is the leading cause of death in children aged 1–14 and the second in 15‐19‐year‐old adolescents in Spain. The Paediatric Population‐Based Cancer Registry of the Community of Madrid was created to monitor its incidence and survival.
Raquel López‐González   +5 more
wiley   +1 more source

Neuroendocrine Tumors (NETs) : A population-based study of incidence and survival in Girona province, 1994-2004 [PDF]

open access: yes, 2012
Els tumors neuroendocrins (TNEs) són un grup de neoplàsies poc freqüents i heterogènies i amb un ampli espectre d'agressivitat. Hi ha molt poca informació epidemiològica a nivell mundial, l'objectiu d'aquest estudi ha estat el de reportar-ne les dades a ...
Alsina Maqueda, Maria   +3 more
core  

Mesenchymal tumours of the mediastinum—part II [PDF]

open access: yes, 2015
This is the second part of a two-part review on soft tissue tumours which may be encountered in the mediastinum. This review is based on the 2013 WHO classification of soft tissue tumours and the 2015 WHO classification of tumours of the lung, pleura ...
Bakker, M.A. (Michael) den   +3 more
core   +5 more sources

Identification of Prognostic Biomarkers in Gene Expression Profile of Neuroblastoma Via Machine Learning

open access: yesPediatric Discovery, Volume 3, Issue 2, June 2025.
This study identified 11 core prognostic biomarkers for neuroblastoma through optimized PPI networks and machine learning, revealing their correlations with chemotherapy and the tumor microenvironment, providing new insights for precision treatment and target development.
Shuxin Tang, Jinhua Fan, Yupeng Cun
wiley   +1 more source

Primary intraspinal ganglioneuroblastoma of the thoracic spine: A rare case report

open access: yesIndian Journal of Pathology and Microbiology, 2012
Cerebral ganglioneuroblastoma is an embryonal tumor of the central nervous system, which has been rarely encountered into the spinal cord. The standard treatment for ganglioneuroblastoma is complete surgical excision. A 15-year old boy was presented with
Kalpalata Tripathy   +4 more
doaj   +1 more source

Biomarker recommendation for PD‐1/PD‐L1 immunotherapy development in pediatric cancer based on digital image analysis of PD‐L1 and immune cells

open access: yesThe Journal of Pathology: Clinical Research, 2020
Anti‐PD‐1/PD‐L1 immunotherapy could offer an alternative to traditional chemo‐ and/or radiotherapy to treat pediatric cancer patients. To unveil the potential benefit of this new therapeutic approach, the prevalence of PD‐L1 and other relevant immune ...
Manuel A Silva   +8 more
doaj   +1 more source

The 2016 World Health Organization Classification of tumours of the Central Nervous System: what the paediatric neuroradiologist needs to know [PDF]

open access: yes, 2016
The recently published 2016 World Health Organization (WHO) classification of tumours of the Central Nervous System (CNS) introduces a number of significant changes from the previous edition.
Carney, O   +4 more
core   +1 more source

Inhibition of Purine Metabolism Promotes the Differentiation of Neuroblastoma Driven by MYCN

open access: yesCancer Medicine, Volume 14, Issue 9, May 2025.
ABSTRACT Background Neuroblastoma (NB), the common extracranial solid tumor in children, is associated with a poor prognosis, particularly in high‐risk patients. MYCN amplification stands as the most prominent molecular hallmark within this high‐risk subgroup. However, MYCN protein is considered “undruggable” due to its lack of a conventional enzymatic
Yufeng Jiang   +14 more
wiley   +1 more source

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