Results 31 to 40 of about 6,776 (214)

Bilateral symmetric dumbbell C1-C2 ganglioneuroma in neurofibromatosis type 1 patient causing spastic quadriparesis

Journal of Spinal Surgery, 2018
Introduction: Ganglioneuroma is a very rare tumor and rarely found bilaterally in association with neurofibromatosis patient. Very few cases of dumbbell ganglioneuroma in the cervical region have been reported in the literature.
Bipin Chaurasia, Dhiman Chowdhury, Ayub Ansari, Robert A Khan, Raushan Chaurasia, Akhlaque H Khan, Ranjit K Chaurasiya, Kanak K Barua, Ramesh Chaurasia, Nazmin A Lopa, Sweta K Chaurasia, Pulak Biswas, Md. Mainul Islam   +12 more
doaj   +1 more source

Giant adrenal ganglioneuroma in children: a case report

Discover Oncology, 2022
Background Ganglioneuromas (GNs) arise from the Schwann cells, ganglion cells, and neuronal tissues, and are extremely rare, slow-growing, benign tumors.
Mingqiu Hu, Zhizhong Tang, Yong Cai, Xiaolu Yuan   +3 more
doaj   +1 more source

Ganglioneuroma of the External Auditory Canal and Middle Ear

Case Reports in Otolaryngology, 2017
Objective. We report an extremely rare case of ganglioneuroma involving the external auditory canal and middle ear. Case Report. Ganglioneuromas are rare benign mature tumors thought to originate from sympathetic ganglions, with the highest incidence in ...
Hesham Saleh Almofada, Michael Steven Timms, M. Anas Dababo   +2 more
doaj   +1 more source

Gangliocytic paraganglioma: case report and review of the literature [PDF]

, 2007
Gangliocytic paraganglioma is a rare tumor, which occurs nearly exclusively in the second portion of the duodenum. Generally, this tumor has a benign clinical course, although rarely, it may recur or metastasize to regional lymph nodes.
Galler, Avi, Witkiewicz, Agnes, Yeo, Charles   +2 more
core   +2 more sources

Adrenal ganglioneuroma with nodal metastases on 123I-MIBG SPECT/CT and 18F-FDG PET/CT

Radiology Case Reports
Ganglioneuroma is a well-differentiated tumor originating from neural crest cells of the sympathetic nervous system. Although benign, a few cases have been reported that ganglioneuroma can metastasize to other sites.
Suzune Tsukamoto, MD, Kazuna Kawabata, MD, PhD, Shunsuke Ito, MD, Saya Ando, MD, Kaori Kuriyama, MD, Shin Morooka, MD, Mototsugu Muramaki, MD, PhD, Mitsunori Kanagaki, MD, PhD, Makoto Hosono, MD, PhD   +8 more
doaj   +1 more source

Massive ganglioneuroma of the parapharyngeal space in a pediatric patient: a case report

The Egyptian Journal of Otolaryngology, 2022
Background Neuroblastic tumors arise from primitive sympathetic ganglion cells and are the most common extracranial solid tumor of childhood. Ganglioneuroma is the most well-differentiated, benign subtype and comprises less than 1% of all soft tissue ...
Swetha Jayavelu, Raleigh Anderson, Garren Low, Karim Asi, Soham Roy   +4 more
doaj   +1 more source

Ganglioneuroma Always A Histopathological Diagnosis [PDF]

, 2011
Neuroblastoma, ganglioneuroblastoma and ganglioneuroma arise from sympathetic tissue in the neck, posterior mediastinum, adrenal gland, retroperitoneum and pelvis Ganglioneuromas are commonly seen in childhood.
K, Balaiah, S, Gnana Prakash, Shetty, Prasad K, Shetty, Prasanna K   +3 more
core   +1 more source

Oncogenic driver and therapeutic target: Prolactin signalling axis in retroperitoneal sarcoma

Clinical and Translational Medicine, Volume 16, Issue 5, May 2026.
Retroperitoneal sarcoma cells can secrete prolactin into the bloodstream, inducing hyperprolactinaemia, which subsequently triggers metabolic reprogramming, such as glucose metabolism. SOX4 can function as a transcription factor that facilitates PRL transcription.
Fu'an Xie, Lingwei Gu, Kunrong Yang, Shuai Wang, Mengmeng Xiao, Guangting Yan, Quan Zhang, Rubing Liang, Aobo Zhuang, Zhe Xi, Yujia Niu, Yanhua Chen, Xiaogang Xia, Linlin Qu, Bin Zhao, Weibing Li, Ting Wu, Chundong Yu, Chenghua Luo, Houzhao Wang, Lanlan Lian, Wengang Li   +21 more
wiley   +1 more source

Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma

Advanced Science, Volume 13, Issue 20, 9 April 2026.
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian, Sreenidhi Mohanvelu, Sheeja Aravindan, Afsana Parveen Jahir Hussain, Sivasubramani Narayanan, Sabir Salim, Loganayaki Periyasamy, Natarajan Aravindan   +7 more
wiley   +1 more source

Targeting ganglioneuromas with mTOR inhibitors

Molecular & Cellular Oncology, 2021
We recently identified activated protein kinase B (PKB/AKT) as a tumorigenic driver in childhood ganglioneuroma. Inhibition of the mechanistic target of rapamycin (mTOR), a serine/threonine kinase downstream of AKT, effectively reduced the tumor burden ...
Ting Tao, Hui Shi, Adam D. Durbin, A. Thomas Look   +3 more
doaj   +1 more source