Results 11 to 20 of about 17,820 (179)

Immunopathogenesis and immunotherapy of Culicoides hypersensitivity in horses: an update

Veterinary Dermatology, Volume 32, Issue 6, Page 579-e156, December 2021., 2021
Culicoides hypersensitivity (CH) is a strongly pruritic dermatitis of horses, characterised histologically by mixed perivascular to diffuse cellular infiltrates of mononuclear cells and eosinophils, and caused by helper T cell (Th)2, immunoglobulin (Ig)E‐mediated reactions to antigens present in the saliva of biting Culicoides midges.
Eliane Marti, Ella N. Novotny, Iva Cvitas, Anja Ziegler, A. Douglas Wilson, Sigurbjörg Torsteinsdottir, Antonia Fettelschoss‐Gabriel, Sigridur Jonsdottir   +7 more
wiley   +1 more source

Obese patients and robotic colorectal surgery: systematic review and meta‐analysis

BJS Open, Volume 4, Issue 6, Page 1042-1053, December 2020., 2020
Obesity is a major health problem that doubles the chance of colorectal cancer. The benefits of robotic surgery for colorectal operations in obese patients versus non‐obese patients are unknown. This meta‐analysis and systematic review highlights that robotic surgery in obese patients is similar and feasible compared with that in non‐obese patients ...
Y. Suwa, M. Joshi, L. Poynter, I. Endo, H. Ashrafian, A. Darzi   +5 more
wiley   +1 more source

Factors associated with metachronous metastases and survival in locally advanced and recurrent rectal cancer

BJS Open, Volume 4, Issue 6, Page 1172-1179, December 2020., 2020
Surgery for locally advanced and recurrent rectal cancer can achieve good survival outcomes. Some histopathological features significantly increase the number of metachronous metastases and shorten survival. Presentation with a synchronous metastasis that is treated successfully significantly increases the number of metachronous metastases and shortens
D. L. H. Baird, C. Kontovounisios, C. Simillis, G. Pellino, S. Rasheed, P. P. Tekkis   +5 more
wiley   +1 more source

Impact of anastomotic leak on long‐term survival in patients undergoing gastrectomy for gastric cancer

BJS (British Journal of Surgery), Volume 107, Issue 12, Page 1648-1658, November 2020., 2020
This study demonstrates that anastomotic leakage leads to prolonged critical care and in‐hospital stay, and is associated with compromised long‐term overall survival. Future research should aim at developing mechanisms and interventions to reduce the risk of anastomotic leaks. Leaks impair outcomes Background The impact of anastomotic leak (AL) on long‐
S. K. Kamarajah, M. Navidi, S. M. Griffin, A. W. Phillips   +3 more
wiley   +1 more source

Machine learning to predict early recurrence after oesophageal cancer surgery

BJS (British Journal of Surgery), Volume 107, Issue 8, Page 1042-1052, July 2020., 2020
Early recurrence after surgery for adenocarcinoma of the oesophagus is common. A risk prediction model was derived using modern machine learning methods that accurately predicts risk of early recurrence using postoperative pathology. Machine learning may help Background Early cancer recurrence after oesophagectomy is a common problem, with an incidence
S. A. Rahman, R. C. Walker, M. A. Lloyd, B. L. Grace, G. I. van Boxel, B. F. Kingma, J. P. Ruurda, R. van Hillegersberg, S. Harris, S. Parsons, S. Mercer, E. A. Griffiths, J. R. O'Neill, R. Turkington, R. C. Fitzgerald, T. J. Underwood, the OCCAMS Consortium, Ayesha Noorani, Rachael Fels Elliott, Paul A.W. Edwards, Nicola Grehan, Barbara Nutzinger, Jason Crawte, Hamza Chettouh, Gianmarco Contino, Xiaodun Li, Eleanor Gregson, Sebastian Zeki, Rachel de la Rue, Shalini Malhotra, Simon Tavaré, Andy G. Lynch, Mike L. Smith, Jim Davies, Charles Crichton, Nick Carroll, Peter Safranek, Andrew Hindmarsh, Vijayendran Sujendran, Stephen J. Hayes, Yeng Ang, Shaun R. Preston, Sarah Oakes, Izhar Bagwan, Vicki Save, Richard J.E. Skipworth, Ted R. Hupp, J. Robert O'Neill, Olga Tucker, Andrew Beggs, Philippe Taniere, Sonia Puig, Timothy J. Underwood, Fergus Noble, James P. Byrne, Jamie J. Kelly, Jack Owsley, Hugh Barr, Neil Shepherd, Oliver Old, Jesper Lagergren, James Gossage, Andrew Davies Fuju Chang, Janine Zylstra, Vicky Goh, Francesca D. Ciccarelli, Grant Sanders, Richard Berrisford, Catherine Harden, David Bunting, Mike Lewis, Ed Cheong, Bhaskar Kumar, Simon L. Parsons, Irshad Soomro, Philip Kaye, John Saunders, Laurence Lovat, Rehan Haidry, Victor Eneh, Laszlo Igali, Michael Scott, Shamila Sothi, Sari Suortamo, Suzy Lishman, George B. Hanna, Christopher J. Peters, Anna Grabowska   +87 more
wiley   +1 more source

Effect of high ligation on survival of patients undergoing surgery for primary colorectal cancer and synchronous liver metastases

BJS Open, Volume 4, Issue 3, Page 508-515, June 2020., 2020
Although R0 surgery is recommended for stage IV colorectal cancer, the degree of lymphadenectomy required has not been established. A multi‐institutional retrospective analysis was done of patients with colorectal cancer and synchronous hepatic metastases who were treated with R0 surgery.
S. Matsui, K. Okabayashi, H. Hasegawa, M. Tsuruta, K. Shigeta, T. Ishida, T. Yamada, T. Kondo, S. Yamauchi, K. Sugihara, Y. Kitagawa   +10 more
wiley   +1 more source

Overall risk and risk factors for metachronous peritoneal metastasis after colorectal cancer surgery: a nationwide cohort study

BJS Open, Volume 4, Issue 2, Page 284-292, April 2020., 2020
In a register‐based study of 22 586 Danish patients with colorectal cancer who had intended curative surgery, a low incidence of metachronous peritoneal metastasis (M‐PM) was found. Risk factors for M‐PM were advanced T and N status and right‐sided colonic tumour.
S. Ravn, U. Heide‐Jørgensen, C. F. Christiansen, V. J. Verwaal, R. H. Hagemann‐Madsen, L. H. Iversen   +5 more
wiley   +1 more source

Topical moistening of mastectomy wounds with diluted tranexamic acid to reduce bleeding: randomized clinical trial

BJS Open, Volume 4, Issue 2, Page 216-224, April 2020., 2020
Moistening surgical wounds with tranexamic acid 25 mg/ml before closure is a simple, low‐cost intervention that reduces bleeding by one‐third and may reduce risk of rebleeding. The effect is comparable to intravenous administration, with a reduced risk of systemic adverse events.
K. Ausen, A. I. Hagen, H. S. Østbyhaug, S. Olafsson, B. J. Kvalsund, O. Spigset, H. Pleym   +6 more
wiley   +1 more source

Trainee performance in radical gastrectomy and its effect on outcomes

BJS Open, Volume 4, Issue 1, Page 86-90, February 2020., 2020
This study of 272 D2 gastrectomies investigated whether trainee involvement was associated with adverse outcomes. No significant difference in morbidity, mortality, operating time, number of nodes resected, hospital stay or predicted 5‐year survival was noted, demonstrating that outcomes are not compromised by supervised trainee involvement.
M. Navidi, A. Madhavan, S. M. Griffin, P. Prasad, A. Immanuel, N. Hayes, A. W. Phillips   +6 more
wiley   +1 more source

Value of individual surgeon performance metrics as quality assurance measures in oesophagogastric cancer surgery

BJS Open, Volume 4, Issue 1, Page 91-100, February 2020., 2020
Annual surgeon‐level metrics demonstrated the greatest variation (fivefold) risking inappropriate target thresholds. Surgeon‐level performance metrics were not associated with survival, suggesting that compound‐level quality assurance provides better overall performance appraisal.
A. G. M. T. Powell, J. Wheat, N. Patel, D. Chan, A. Foliaki, S. A. Roberts, W. G. Lewis, on behalf of the South‐East Wales Oesophagogastric Cancer Collaborative, G. Blackshaw, G. Clark, A. Christian, X. Escofet, A. Foliaki, T. Havard, M. Henwood, J. Witherspoon, W. G. Lewis   +16 more
wiley   +1 more source